Kazuhiro Mitsumura, M. Ōsaki, M. Hara, S. Kinoshita, Keitaro Nagano, Akio Hatanaka, M. Shimoda, T. Hashimoto, Yusuke Yamamoto, Hideki Fujihara, W. Nishijima, Eikichi Tokunaga
{"title":"Mucosal malignant melanoma of the head and neck: Clinical analysis of 12 cases","authors":"Kazuhiro Mitsumura, M. Ōsaki, M. Hara, S. Kinoshita, Keitaro Nagano, Akio Hatanaka, M. Shimoda, T. Hashimoto, Yusuke Yamamoto, Hideki Fujihara, W. Nishijima, Eikichi Tokunaga","doi":"10.5981/jjhnc.46.365","DOIUrl":null,"url":null,"abstract":"The present report describes the treatment of 12 patients with primary mucosal malignant melanoma of the head and neck who visited our department between 2011 and 2017. There were 6 men and 6 women, aged 61-90 years (median, 76.5 years), and the observation period was 7-165 months (median, 37 months). Further, 11 patients (92%) presented with primary lesions located in the nasal/paranasal cavities and 1 patient (8%) with the primary lesion located in the oral cavity. The 3-year overall survival rate, as assessed using the Kaplan-Mei-er method, was 56%. Among 8 patients with primary malignant melanoma of the nasal/paranasal cavities who underwent carbon-ion radiotherapy or surgery as a radical treatment, the 3-year local control and 3-year recur-rence-free survival rates were 56% and 38%, respectively. The local control rate was higher in the carbon-ion radiotherapy group. In 12 patients, the 5-year incidence of distant metastasis was as high as 75, and","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"40 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Japanese Journal of Head and Neck Cancer","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5981/jjhnc.46.365","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
The present report describes the treatment of 12 patients with primary mucosal malignant melanoma of the head and neck who visited our department between 2011 and 2017. There were 6 men and 6 women, aged 61-90 years (median, 76.5 years), and the observation period was 7-165 months (median, 37 months). Further, 11 patients (92%) presented with primary lesions located in the nasal/paranasal cavities and 1 patient (8%) with the primary lesion located in the oral cavity. The 3-year overall survival rate, as assessed using the Kaplan-Mei-er method, was 56%. Among 8 patients with primary malignant melanoma of the nasal/paranasal cavities who underwent carbon-ion radiotherapy or surgery as a radical treatment, the 3-year local control and 3-year recur-rence-free survival rates were 56% and 38%, respectively. The local control rate was higher in the carbon-ion radiotherapy group. In 12 patients, the 5-year incidence of distant metastasis was as high as 75, and