Textural and sensory characterization of carbomeric gels with panthenol

IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL
M. Martinović, Nenad Stojanović, I. Nešić
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引用次数: 1

Abstract

Introduction. The aim of this study was to evaluate the influence of the carbomer concentration (used as the gelling agent, in the range 0.5 - 2.0%) on textural and sensory characteristics of gels with 3% panthenol using sensory analysis as subjective and texture analysis as an objective assessment method. An active substance in the gels was panthenol, which also acted as a neutralizing agent of the carbomer. Participants and methods. Twenty female panelists, aged between 20 and 36, participated in the sensory study and had to fulfill a questionnaire regarding product attributes before, during and after application on the skin. Texture analysis was performed on CT3 Texture Analyzer, after each week for a month, and the following parameters were calculated: hardness cycle 1, hardness cycle 2, cohesiveness, adhesiveness, resilience and springiness. Results. The results showed that gels were stable over time and the structure of the gels was preserved regardless of compression. An increase in hardness and resilience was followed by an increase in the concentration of carbomer, while adhesiveness, cohesiveness and springiness did not differ much among different gels. The same trend was noticed when gels were compared during time. Sensory analysis confirmed findings of texture analysis and showed that with the increment of carbomer concentration, stickiness and density also enhanced, while absorption rate and spreadability decreased. Gel with 1% carbomer was chosen by the majority of panelists as favorite and as a gel they would regularly use. Conclusion. The methods of textural and sensory analysis represent valuable approaches in drug/cosmetic product design because they offer insight in the compliance of patients/consumers.
泛醇碳聚物凝胶的结构和感官特性
介绍。本研究的目的是评价卡波姆浓度(用作胶凝剂,在0.5 - 2.0%范围内)对3%泛醇凝胶的结构和感官特性的影响,以感官分析为主观评价方法,结构分析为客观评价方法。凝胶中的一种活性物质是泛醇,它也是卡波姆的中和剂。参与者和方法。20名年龄在20至36岁之间的女性小组成员参加了感官研究,并在皮肤上使用产品之前,期间和之后填写了一份关于产品属性的问卷。在CT3织构分析仪上进行织构分析,每周一次,连续一个月,计算硬度周期1、硬度周期2、内聚性、黏附性、回弹性、弹性等参数。结果。结果表明,随着时间的推移,凝胶是稳定的,无论压缩凝胶的结构保持不变。硬度和回弹性的增加伴随着卡波姆浓度的增加,而黏附性、内聚性和弹性在不同凝胶之间差异不大。同样的趋势也被注意到,当凝胶在一段时间内进行比较。感官分析证实了织构分析的结果,表明随着卡波姆浓度的增加,黏性和密度增加,吸收率和铺展性降低。含有1%卡波姆的凝胶被大多数小组成员选为他们最喜欢的凝胶,也是他们经常使用的凝胶。结论。质地和感官分析方法代表了药物/化妆品设计中有价值的方法,因为它们提供了对患者/消费者依从性的洞察。
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来源期刊
Acta Facultatis Medicae Naissensis
Acta Facultatis Medicae Naissensis MEDICINE, GENERAL & INTERNAL-
CiteScore
0.70
自引率
0.00%
发文量
13
审稿时长
12 weeks
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