Stress Axis Response to Aerobic Exercise in Chronic Obstructive Pulmonary Disease Patients

Q3 Medicine

Postepy Rehabilitacji Pub Date : 2022-01-01 DOI:10.5114/areh.2022.123180

Ali Mohamed Ali Ismail

{"title":"Stress Axis Response to Aerobic Exercise in Chronic Obstructive Pulmonary Disease Patients","authors":"Ali Mohamed Ali Ismail","doi":"10.5114/areh.2022.123180","DOIUrl":null,"url":null,"abstract":"Introduction: COVID mortality is particularly high among patients with comorbidities;this may be due to psychological stress caused by overactivation of the stress axis. The study investigates the effect of home-based physical activity (HBPA) on the stress axis in patients with chronic obstructive pulmonary disease (COPD). Material and methods: Forty men aged 55–68 years with stable COPD were randomly divided into study or control groups. The study group (n = 20) received eight-week HBPA, three sessions per week, while the control group (n = 20) did not. The following measurements were taken for both groups: body mass index (BMI), pulmonary function test (PFT), cortisol, interleukin-8 (IL-8), health-related quality of life assessed as total St. George's Respiratory Questionnaire (SGRQ) score, hospital anxiety and depression scale score (HADS), and 6-minute walking test (6MWT). Results: All variables of the control group showed non-significant improvement. Significant improvements in cortisol (262.15 ± 25.08 vs 219.80 ± 30.68 ng/mL;p < 0.001), IL-8 (15.00 ± 5.64 vs 12.26 ± 5.07 pg/ml;p < 0.001), HADS (7.85 ± 2.56 vs 5.36 ± 2.68 and 8.75 ± 2.46 vs 6.60 ± 2.70;p < 0.001 for depression and anxiety subscales, respectively), SGRQ total score (40.50 ± 11.70 vs 35.90 ± 11.75;p < 0.001), and 6MWT (514.85 ± 22.49 vs 575.90 ± 34.37;p < 0.001) were found in the study group over time. No change was observed for BMI and PFT. Conclusions: HBPA is a good tool for improving cortisol, IL-8, HADS, SGRQ, and 6MWT level in COPD patients, especially during the COVID pandemic. © 2022 European Journal of Analytic Philosophy. All rights reserved.","PeriodicalId":52524,"journal":{"name":"Postepy Rehabilitacji","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"7","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Postepy Rehabilitacji","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5114/areh.2022.123180","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 7

Abstract

Introduction: COVID mortality is particularly high among patients with comorbidities;this may be due to psychological stress caused by overactivation of the stress axis. The study investigates the effect of home-based physical activity (HBPA) on the stress axis in patients with chronic obstructive pulmonary disease (COPD). Material and methods: Forty men aged 55–68 years with stable COPD were randomly divided into study or control groups. The study group (n = 20) received eight-week HBPA, three sessions per week, while the control group (n = 20) did not. The following measurements were taken for both groups: body mass index (BMI), pulmonary function test (PFT), cortisol, interleukin-8 (IL-8), health-related quality of life assessed as total St. George's Respiratory Questionnaire (SGRQ) score, hospital anxiety and depression scale score (HADS), and 6-minute walking test (6MWT). Results: All variables of the control group showed non-significant improvement. Significant improvements in cortisol (262.15 ± 25.08 vs 219.80 ± 30.68 ng/mL;p < 0.001), IL-8 (15.00 ± 5.64 vs 12.26 ± 5.07 pg/ml;p < 0.001), HADS (7.85 ± 2.56 vs 5.36 ± 2.68 and 8.75 ± 2.46 vs 6.60 ± 2.70;p < 0.001 for depression and anxiety subscales, respectively), SGRQ total score (40.50 ± 11.70 vs 35.90 ± 11.75;p < 0.001), and 6MWT (514.85 ± 22.49 vs 575.90 ± 34.37;p < 0.001) were found in the study group over time. No change was observed for BMI and PFT. Conclusions: HBPA is a good tool for improving cortisol, IL-8, HADS, SGRQ, and 6MWT level in COPD patients, especially during the COVID pandemic. © 2022 European Journal of Analytic Philosophy. All rights reserved.

查看原文本刊更多论文

慢性阻塞性肺疾病患者有氧运动的应激轴反应

导语:COVID患者的死亡率在合并症中特别高，这可能是由于压力轴过度激活引起的心理压力。本研究旨在探讨以家庭为基础的体力活动(HBPA)对慢性阻塞性肺疾病(COPD)患者应激轴的影响。材料与方法:40例55 ~ 68岁稳定期COPD男性随机分为研究组和对照组。研究组(n = 20)接受为期8周的HBPA治疗，每周3次，而对照组(n = 20)则没有。对两组进行以下测量:身体质量指数(BMI)、肺功能测试(PFT)、皮质醇、白细胞介素-8 (IL-8)、健康相关生活质量评估(圣乔治呼吸问卷(SGRQ)总分、医院焦虑和抑郁量表评分(HADS)和6分钟步行测试(6MWT)。结果:对照组各项指标均无明显改善。显著提高皮质醇(262.15±25.08 vs 219.80±30.68 ng / mL; p < 0.001),引发(15.00±5.64 vs 12.26±5.07 pg / mL; p < 0.001),有(7.85±2.56 vs 5.36±2.68,8.75±2.46 vs 6.60±2.70;p < 0.001抑郁和焦虑量表分别),SGRQ总得分(40.50±11.70 vs 35.90±11.75;p < 0.001),和6 mwt(514.85±22.49 vs 575.90±34.37;p < 0.001)被发现在学习小组。BMI和PFT未见变化。结论:HBPA是改善COPD患者皮质醇、IL-8、HADS、SGRQ和6MWT水平的良好工具，特别是在COVID大流行期间。©2022欧洲分析哲学杂志。版权所有。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Postepy Rehabilitacji Medicine-Rehabilitation

CiteScore

1.10

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： Advances in Rehabilitation is not only directed to representatives of biological and medical sciences, specialists from almost all fields of medicine, such as cardiology, neurology, orthopedics, traumatology and internal diseases, have been published in it. The journal contains papers concerning psychological, sociological, and occupational rehabilitation, along with articles which deal with organization and marketing. The journal is also dedicated to the ethical problems of rehabilitation. A significant part of the published papers have focused on the problems of sport and physical activity for people with disabilities