Atención e inhibición en el Deterioro Cognitivo Leve y

C. Zancada-Menendez, P. Sampedro-Piquero, A. Begega, Laudino López, J. Arias
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Abstract

Mild cognitive impairment is understood as a cognitive deficit of insufficient severity to fulfil the criteria for Alzheimer’s disease. Many studies have attempted to identify which cognitive functions are most affected by this type of impairment and which is the most sensitive neuropsychological test for early detection. This study investigated sustained and selective attention, processing speed, and the inhibition process using a sample of people divided into three groups mild cognitive impairment, Alzheimer disease and cognitively healthy controls selected and grouped based on their scores in the Mini Mental State Examination and Cambridge Cognitive Examination-revised. Three tests from the Cambridge Neuropsychological Test Automated Battery (Motor Screening Task, Stop Signal Task and Reaction time) were used as well as the d2 attention test. The results show that that participants with mild cognitive impairment and Alzheimer disease showed lower levels of concentration compared with the cognitively healthy controls group in the d2 test and longer reaction times in the Cambridge Neuropsychological Test Automated Battery, although the differences were not marked in the latter test. The impairments in basic cognitive processes, such as reaction time and sustained attention, indicate the need to take these functions into account in the test protocols when discriminating between normal aging and early and preclinical dementia processes.
注意和抑制轻度认知障碍和
轻度认知障碍被理解为严重程度不足以满足阿尔茨海默病标准的认知缺陷。许多研究试图确定哪些认知功能受这种类型的损害影响最大,哪些是早期检测最敏感的神经心理学测试。本研究以轻度认知障碍者、阿尔茨海默病患者和认知健康对照组为研究对象,根据他们在迷你精神状态检查和剑桥认知检查的分数进行分组,研究了持续和选择性注意、加工速度和抑制过程。使用了剑桥神经心理测试自动电池中的三个测试(运动筛选任务、停止信号任务和反应时间)以及d2注意测试。结果显示,与认知健康的对照组相比,患有轻度认知障碍和阿尔茨海默病的参与者在d2测试中表现出较低的注意力水平,在剑桥神经心理测试自动化电池中表现出较长的反应时间,尽管在后一项测试中差异不明显。基本认知过程的损伤,如反应时间和持续注意力,表明在区分正常衰老和早期和临床前痴呆过程时,需要在测试方案中考虑这些功能。
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