Discovering Pathologies in the Anatomy Lab: The Case of Brachial Plexopathy Mimicking Neurological Thoracic Outlet Syndrome

Ryley Mancine, P. Kowalski, W. McMillan, N. Geske, L. Kujjo
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Abstract

CONTEXT Well-established human anatomy labs with access to expert faculty are exceedingly valuable tools to medical student education. In this manuscript, we detail an infero-lateral subclavicular lipoma which was discovered as a result of the utilization of both those labs and expert faculty. This lipoma may have caused brachial plexopathy or may serve as an unusual cause of neurologic thoracic outlet syndrome (NTOS) due to the location of the mass. EDUCATIONAL CASE PRESENTATION During prosection of a donor in the human anatomy lab, a mass was discovered by a medical student. This medical student utilized the human anatomy lab faculty members and resources to identify the mass as a lipoma. The lipoma compressed the lateral cord of the brachial plexus and the suprascapular nerve, but no diagnosis of NTOS or brachial plexopathy was made during the life of the donor, nor was any surgical intervention indicated. Removal of the lipoma immediately relieved stress upon the nerves. Histochemical analysis confirmed the diagnosis of a lipoma and demonstrated almost only mature adipocytes. CONCLUSION The authors concluded that the lipoma of this patient was not identifiable with computerized tomography imaging modalities, despite ultrasound demonstrating a hyperechoic outline of the mass in the cadaver of the patient. It is very likely that this lipoma had not been diagnosed previously due to the atypical location of the tumor. Equally, typical surgical methods associated with brachial plexopathy or NTOS treatment would be difficult or more complicated, due to the lateral and inferior location of the lipoma. Physicians treating thoracic outlet syndrome-type symptoms without resolution should consider potential non-malignant obstruction located outside the thoracic outlet, toward the extremity. Deep palpatory methods and physical therapy should be considered until diagnosis is certain, as ultrasound would be difficult and typical transaxillary surgical methods would be nonhelpful. Medical students and early-career residents and physicians should be aware of the resources provided to them via campus human anatomy laboratories which they may utilize to further their understanding and knowledge of specific pathologies.
解剖实验室病理发现:模拟神经性胸廓出口综合征的臂丛病病例
背景:完善的人体解剖学实验室是医学学生教育的极有价值的工具。在这篇手稿中,我们详细介绍了一个下外侧锁骨下脂肪瘤,这是由于这些实验室和专家教师的利用而发现的。脂肪瘤可能引起臂丛病,也可能由于肿块的位置而成为神经性胸椎出口综合征(NTOS)的罕见病因。在人体解剖实验室对一名捐赠者进行检控时,一名医学生发现了一个肿块。这名医学生利用人体解剖实验室的教员和资源来确定肿块为脂肪瘤。脂肪瘤压迫臂丛外侧束和肩胛上神经,但在供者的一生中没有诊断为NTOS或臂丛病,也没有任何手术干预。脂肪瘤的切除立即减轻了神经的压力。组织化学分析证实了脂肪瘤的诊断,显示几乎只有成熟的脂肪细胞。结论:尽管超声在患者尸体上显示肿块的高回声轮廓,但该患者的脂肪瘤无法通过计算机断层成像方式识别。由于肿瘤的非典型位置,这种脂肪瘤很可能以前没有被诊断出来。同样,由于脂肪瘤位于外侧和下方,与臂丛病或NTOS治疗相关的典型手术方法也很困难或更复杂。如果胸廓出口综合征型症状没有得到缓解,医生应考虑胸廓出口外、向肢体方向的潜在非恶性梗阻。在确定诊断之前,应考虑深层触诊方法和物理治疗,因为超声检查很困难,典型的经腋窝手术方法也没有帮助。医学生、早期住院医师和医生应该了解通过校园人体解剖学实验室提供给他们的资源,他们可以利用这些资源来进一步理解和了解特定的病理学。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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