Iposodiemia, idroureteronefrosi e infezione delle vie urinarie: pensiamo allo pseudoipoaldosteronismo

Abstract

Hyponatremia is a frequent finding in pediatric emergency department. Association of hyponatremia with hyperkalemia and metabolic acidosis, in a context of urinary tract infection and/or uropathy, may lead to suspicion of secondary pseudohypoaldosteronism (S-PHA). We describe a 8 month old child evaluated for weight loss, severe hyponatremia, mild hyperkalemia and metabolic acidosis. Further evaluation showed elevation in renin and aldosterone concentrations, urinary tract infection and hydroureteronephrosis, suggesting S-PHA diagnosis.