Comparison of Serum D-dimer, Fibrinogen and Platelet Levels in Pregnant Women with COVID-19 Symptoms According to PCR Positivity or PCR Negativity: A Case-Control Study

Abstract

Objective: The diagnosis and treatment of coronavirus disease-2019 (COVID-19) infection may be delayed in pregnant women because of the non-specific symptoms and limited application of the necessary radiological tests. The aim of this study was to compare the serum D-dimer, fibrinogen, and platelet levels in pregnant patients with COVID-19 symptoms and polymerase chain reaction (PCR) positivity or PCR negativity. Material and Methods: The study included 100 pregnant women who presented at the Gynaecology and Obstetrics Clinic of Tokat State Hospital between April 2020 and December 2020 with symptoms of COVID-19 infection (fever, cough, shortness of breath). Half of the patients were COVID-19 PCR positive and half were negative. The groups were compared in respect of age, gravida, gestational week, COVID-19 symptoms (fever, cough, shortness of breath), serum D-dimer, fibrinogen, and platelet values.