Factors Associated with High Blood Pressure in People Living with HIV at the National Teaching Hospital Hubert Koutoukou Maga and Cotonou Teaching Hospital of the Armed Forces

Azon-Kouanou Angèle, Ayihounton Gaël, Derrick Mémoire Dégbo, A. Anthelme, Sokadjo Yves Morel, Missiho Mahoutin Sèmassa Ghislain, F. Géoffroy, Z. Marcel, Houngbé Fabien
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Abstract

In Benin Republic, few data are available on the prevalence and determinants of arterial hypertension (AH) in people living with the human immunodeficiency virus (PLWHA). The present study was conducted in two outpatient treatment centers for PLWHA in Cotonou and was conducted from June 19 to July 04, 2019 with 314 PLWHA. We performed descriptive statistics and logistic regression for the estimates. The prevalence of high blood pressure (HBP) among PLWHA was 41.4% [CI (95%): (35.9 - 47)]. In univariate analysis: age, smoking, alcoholism, physical inactivity, family history of hypertension, personal history of diabetes, obesity, and total and LDL (low density li-poprotein) hypercholesterolemia were significantly associated with HBP. No association was found with duration of HIV (human immunodeficiency virus) infection, time to ARV (antiretrovirals) exposure, and treatment regi-men. In multivariate analysis, age, sex, smoking, family history of hypertension, and total hypercholesterolemia remained associated with HBP. In con-clusion, the prevalence of HBP in PLWHA was very high compared with the results in the general population, and the same risk factors described in the general population were found but with a more marked hypertense potential.
Hubert Koutoukou Maga国家教学医院和Cotonou武装部队教学医院的HIV感染者高血压相关因素
在贝宁共和国,关于人类免疫缺陷病毒(PLWHA)感染者动脉高血压(AH)患病率和决定因素的数据很少。本研究于2019年6月19日至7月4日在科托努的两个PLWHA门诊治疗中心进行,共有314名PLWHA患者。我们对估计进行了描述性统计和逻辑回归。PLWHA患者中高血压(HBP)患病率为41.4% [CI(95%): 35.9 - 47]。在单因素分析中,年龄、吸烟、酗酒、缺乏运动、高血压家族史、糖尿病个人史、肥胖、总胆固醇和LDL(低密度脂蛋白)高胆固醇血症与HBP显著相关。未发现与HIV(人类免疫缺陷病毒)感染持续时间、抗逆转录病毒药物暴露时间和治疗方案相关。在多变量分析中,年龄、性别、吸烟、高血压家族史和总高胆固醇血症仍与HBP相关。综上所述,与普通人群相比,艾滋病患者的HBP患病率非常高,并且发现了与普通人群相同的危险因素,但高血压电位更为明显。
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