Evaluation of serum mineral status in dermatological disorders of dogs

G. Sai, V. Babitha, V. Ramnath, V. Beena, N. Unny
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Abstract

The study was undertaken to evaluate serum mineral status, specifically zinc, copper and selenium in dogs affected with dermatological disorders in comparison to normal healthy dogs. The study included 40 dogs of 2-5 years of age with skin diseases presented to University Veterinary Hospitals at Mannuthy and Kokkalai under the Kerala Veterinary and Animal Sciences University, and ten apparently healthy dogs brought to the hospital for routine health check-up which served as control. Serum concentrations of the three minerals were compared not only between normal and dogs with skin diseases as a whole but also between individual skin diseases- six different skin diseases- with the control group. On comparing the dogs with skin ailments (n=40) and control group, the serum mineral levels analysed through Atomic Absorption Spectrophotometry (AAS) revealed that the concentration of zinc was significantly lower (p<0.01) in the diseased group (0.53 ± 0.04 mg/L) of dogs (n=40) than the control group (1.11 ± 0.09 mg/L) and the serum copper concentration was also significantly reduced (p<0.05) in diseased dogs (0.91 ± 0.08 mg/L) with respect to the control animals (1.23 ± 0.11 mg/L). The serum selenium concentration of diseased group of animals(n=40), however failed to show any significant difference from the control group of animals. The outcome of the study suggests a need for supplementation of zinc and copper in dogs with skin ailments like canine demodicosis that relapse even after prolonged therapy with acaricides.
犬皮肤病患者血清矿物质状态的评价
该研究旨在评估患有皮肤病的狗与正常健康狗的血清矿物质状态,特别是锌、铜和硒。该研究包括40只2-5岁患有皮肤病的狗,送到喀拉拉邦兽医和动物科学大学下属的Mannuthy和Kokkalai大学兽医医院,以及10只明显健康的狗被带到医院进行常规健康检查,作为对照。这三种矿物质的血清浓度不仅在正常狗和患有皮肤病的狗之间进行了比较,而且还在患有六种不同皮肤病的狗与对照组之间进行了比较。用原子吸收分光光度法(AAS)对40只皮肤病犬与对照组进行比较,结果显示,40只皮肤病犬的血清矿物质含量(0.53±0.04 mg/L)明显低于对照组(1.11±0.09 mg/L),铜含量(0.91±0.08 mg/L)明显低于对照组(1.23±0.11 mg/L) (p<0.05)。而患病组动物(n=40)的血清硒浓度与对照组动物没有显著差异。研究结果表明,患有犬蠕虫病等皮肤病的狗需要补充锌和铜,即使长期使用杀螨剂治疗也会复发。
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