Phthalates in our food

L. Birnbaum, T. Schug
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引用次数: 14

Abstract

Phthalates are a group of chemicals used to make plastics softer and more flexible. They are used in hundreds of products, such as vinyl flooring, adhesives, detergents, lubricating oils, automotive plastics, plastic clothes (raincoats) and personal-care products (soaps, shampoos, hair sprays and nail polishes). People are exposed to phthalates by eating and drinking foods that have been in contact with containers and products containing phthalates. To a lesser extent, exposure can occur from breathing in air that contains vapors or dust contaminated with phthalate particles. Once phthalates enter a person's body, they are converted into breakdown products that pass out quickly in urine. However, biomonitoring studies that measure urine metabolites in humans show widespread exposure to phthalates. Phthalates have been labeled as potential endocrine disrupting chemicals (EDCs) because studies have demonstrated that they interfere with hormones of the reproductive system. Recently, we reported for the first time concentrations of phthalates in United States food and used these finding to estimate dietary phthalate intake.1 The estimated intakes for individual phthalates in our study were more than an order of magnitude lower than EPA Reference Doses (RfDs), but more studies are needed to evaluate cumulative exposure to phthalates as byproducts of food consumption.
我们食物中的邻苯二甲酸盐
邻苯二甲酸盐是一组化学物质,用于使塑料更柔软、更有弹性。它们被用于数百种产品,如乙烯基地板、粘合剂、洗涤剂、润滑油、汽车塑料、塑料衣服(雨衣)和个人护理产品(肥皂、洗发水、发胶和指甲油)。人们通过食用和饮用接触过含有邻苯二甲酸盐的容器和产品的食物而接触到邻苯二甲酸盐。在较小程度上,吸入含有被邻苯二甲酸盐颗粒污染的蒸汽或灰尘的空气可能会发生接触。一旦邻苯二甲酸盐进入人体,它们就会转化为分解产物,迅速随尿液排出。然而,测量人类尿液代谢物的生物监测研究表明,邻苯二甲酸盐的暴露范围很广。邻苯二甲酸酯被标记为潜在的内分泌干扰化学物质(EDCs),因为研究表明它们会干扰生殖系统的激素。最近,我们首次报道了美国食品中邻苯二甲酸盐的浓度,并利用这些发现来估计饮食中邻苯二甲酸盐的摄入量在我们的研究中,个体邻苯二甲酸盐的估计摄入量比EPA参考剂量(rfd)低一个数量级以上,但需要更多的研究来评估作为食物消费副产品的邻苯二甲酸盐的累积暴露。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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