Different Measurements of Body Fatness and Cardiovascular Risk in Community Dwelling Old Adults

O. Geirsdottir, M. Chang, P. Jonsson, I. Thorsdottir, A. Ramel
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Abstract

Body mass index (BMI) does not necessarily predict cardiovascular disease in old populations which has been called obesity paradox. The aims of the present study were to investigate 1) the associations between BMI and body fat in old adults, and 2) whether more sophisticated measures of body fat are stronger associated with cardiovascular risk than BMI. In the current cross-sectional analysis, the participants‘(N=232, 65-92 years) body fatness was estimated using BMI, waist-circumference, DXA (fat mass, visceral fat mass) and cardiovascular risk factors (blood lipids, glucose metabolism, blood pressure) were assessed. BMI correlated highly with fat mass measured by DXA independently from age tertiles and in both genders. In general, body fatness was positively related to several cardiovascular risk factors and this was persistently observed for all the different measures of body fatness. However, fat measures were not associated with total cholesterol or LDL. Sensitivity analysis indicated that BMI ≥ 25 identifies 70-100% of participants with the above mentioned cardiovascular risk factors outside normal range. We conclude in BMI is highly correlated with body fatness in old Icelandic adults. DXA measurement of body fatness is not better in estimating cardiovascular risk in old adults compared to simple BMI.
社区居住老年人体脂和心血管风险的不同测量方法
身体质量指数(BMI)并不一定能预测老年人的心血管疾病,这被称为肥胖悖论。本研究的目的是调查1)老年人身体质量指数和身体脂肪之间的关系,以及2)更复杂的身体脂肪测量是否比身体质量指数与心血管风险的关系更强。在当前的横断面分析中,通过BMI、腰围、DXA(脂肪量、内脏脂肪量)和心血管危险因素(血脂、葡萄糖代谢、血压)评估参与者(N=232, 65-92岁)的体脂。BMI与DXA测量的脂肪质量高度相关,独立于年龄分位数和性别。总的来说,身体肥胖与几个心血管危险因素呈正相关,这在所有不同的身体肥胖测量中都持续观察到。然而,脂肪测量与总胆固醇或低密度脂蛋白无关。敏感性分析表明,BMI≥25表明70-100%的受试者存在正常范围外的上述心血管危险因素。我们得出结论,BMI与冰岛老年人的体脂高度相关。与简单BMI相比,DXA测量体脂在估计老年人心血管风险方面并不更好。
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