Predictors of Time to Recovery from a Surgical Repair of Obstetric Fistula at Mekelle Hamlin Fistula Center, Tigray, Ethiopia

S. Hailu
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引用次数: 2

Abstract

Background: Ethiopia is one of the high fistula burdened countries in the world with an annual occurrence of 3,500 new and existence of 37,500 untreated obstetric fistula cases. Studies conducted in this area focus on determinants of obstetric fistula before surgical repair and researches addressing the associated factors are limited. Objective: To estimate time to recovery from a surgical repair of obstetric fistula and its associated factors among patients treated at Mekelle Hamlin Fistula Center. Methods: The data represent random samples of 306 fistula patients treated at Mekelle Hamlin Fistula Center from February 2006 to December 2014. Patients’ background characteristics, obstetric and perioperative information was collected. Comparison of survival time and selection of candidates among categorical variables were done using Kaplan-Meier curve and log rank test. Variables with p-value ≤ 0.25 in bivariate analysis were included in multivariable analysis. Cox proportional hazard assumption, Confounding, Interaction, Multicollinearity and Model fitness were tested: Tables, figures, hazard ratios and 95% confidence intervals were used to present results. Results: The patients were followed for 6657 person days at risk, the median recovery time was 20 days. The overall recovery rate was 2.5 cases per 100 person days. Multivariable Cox proportional hazard model result showed labor duration of two or more days (AHR=0.73, 95% CI=0.53, 0.99) and post-operative bladder catheterization longer than 14 or more days (AHR=0.45, 95% CI=0.32, 0.62) were factors negatively associated with recovery time from obstetric fistula surgery. Conclusion and recommendations: women who experienced labor of two or more days and post-operative bladder drainage for more than two or more weeks took longer time to recover after the repair. Therefore, Decision makers, Health care professionals, Stakeholders and Researchers should give emphasis on activities that reduce delays’ in decision making, delays’ in giving urgent intervention and delays’ in reaching health institutions that contributes in reducing complications of prolonged labor ultimately obstetric fistula.
埃塞俄比亚提格雷Mekelle Hamlin瘘管中心产科瘘手术修复恢复时间的预测因素
背景:埃塞俄比亚是世界上瘘管病负担高的国家之一,每年有3500例新发病例和37500例未经治疗的产科瘘病例。在这一领域进行的研究侧重于手术修复前产科瘘的决定因素,解决相关因素的研究有限。目的:评估在Mekelle Hamlin产科瘘中心治疗的患者手术修复产科瘘的恢复时间及其相关因素。方法:数据为2006年2月至2014年12月在Mekelle Hamlin瘘管中心随机抽取的306例瘘管患者。收集患者的背景特征、产科及围手术期信息。采用Kaplan-Meier曲线和log rank检验比较分类变量的生存时间和候选变量的选择。双变量分析中p值≤0.25的变量纳入多变量分析。对Cox比例风险假设、混杂、相互作用、多重共线性和模型适应度进行检验:使用表格、图表、风险比和95%置信区间来表示结果。结果:随访时间为6657人日,中位康复时间为20天。总治愈率为每100人日2.5例。多变量Cox比例风险模型结果显示,分娩时间2天及以上(AHR=0.73, 95% CI=0.53, 0.99)和术后膀胱导尿时间超过14天(AHR=0.45, 95% CI=0.32, 0.62)与产科瘘手术恢复时间呈负相关。结论和建议:分娩2天及以上,术后膀胱引流2周及以上的患者,术后恢复时间较长。因此,决策者、保健专业人员、利益攸关方和研究人员应重点开展活动,减少决策方面的延误、提供紧急干预措施方面的延误和到达保健机构方面的延误,从而有助于减少长时间分娩最终导致产科瘘管病的并发症。
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