Ordinary Citizens' Expectations for Regenerative Medicine and Induced Pluripotent Stem Cells Researches in Japan

Y. Takimoto, E. Nakazawa, A. Tsuchiya, Akabayashi Akira
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Abstract

Objective: In order to examine people’s expectations for regenerative medicine and iPS cells researches in Japan, we conducted an attitude survey not only among ordinary citizens but also among patients with age-related macular degeneration. Methods: 2,656 ordinary citizens, 445 age-related macular degeneration patients, and families of 210 agerelated macular degeneration patients answered 5 question items. Results: Knowledge of iPS cell research, expectations for treatment using iPS cells, and Information acquisition of studies using iPS cells were significantly higher among patients and their families, in comparison with citizens. Regarding iPS cells researches, the ordinary citizens were favor of promoting development of therapeutic drugs for intractable diseases rather than "organ regeneration, including the liver and kidney" and "creation of sperm and ova for assisted reproductive technology". Conclusions: Expectations for regenerative medicine, using iPS cells, were greater both among individuals involved in the disease and ordinary citizens. Especially, they count on development of therapeutic drugs for intractable diseases.
日本普通市民对再生医学和诱导多能干细胞研究的期望
目的:为了了解日本民众对再生医学和iPS细胞研究的期望,我们不仅对普通民众进行了态度调查,还对老年性黄斑变性患者进行了态度调查。方法:2656名普通市民、445名老年性黄斑变性患者、210名老年性黄斑变性患者家属回答5个问题项。结果:与普通市民相比,患者及其家属对iPS细胞研究的了解程度、对使用iPS细胞进行治疗的期望以及对使用iPS细胞进行研究的信息获取明显更高。对于诱导多能干细胞的研究,普通市民更倾向于促进治疗顽固性疾病的药物的开发,而不是“器官再生,包括肝和肾”和“为辅助生殖技术创造精子和卵子”。结论:对于使用iPS细胞的再生医学,患者和普通市民的期望都更高。特别是,他们指望开发治疗顽固性疾病的药物。
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