{"title":"What is Missing in STD Screening in Hong Kong","authors":"C. Chan, W. Chan, C. H. Cheng, P. Xia","doi":"10.3844/AMJSP.2016.13.18","DOIUrl":null,"url":null,"abstract":"This retrospective analysis was to study the prevalence of Sexually Transmitted Diseases (STD) in a Reproductive Medical Center in Hong Kong. A total of 1190 patients were included in this study. Group 1A, couples had no symptoms but presented with subinfertility; Group 1B, the subfertile couples were positive for either Chlamydia trachomatis (CT) or Ureaplasma urealyticum (UU); Group 2, couples with symptoms were offered full STD screening including CT, UU, Mycoplasma hominis (MH), Neisseria gonorrhoea (NG), Syphilis, Herpes Simplex Virus 1 and 2. The methods of ELISA and quantitative real-time PCR were used for these analyses. Group 1A: UU detection rates in both male and female (13.84 v.s. 37.07%) were significantly higher than that of CT (5.65 v.s. 5.57%); Group 1B and Group 2: For those who had Full STD check, UU and MH detection rates were significantly higher than that of CT (35, 13.7 and 7.1% respectively). Over 47% of patients showed positive for one or more organism. In the subfertile couples, the UU and CT detection rates were much higher in females than those in males. Both semen and urine samples gave the same rates of infection among CT, UU, NG and MH. U. urealyticum infection rate rather than Chlamydis trachomatis infection is highest in Hong Kong. The infection rate in females is higher than in males. The detection rates in semen and urine samples in males are similar.","PeriodicalId":89887,"journal":{"name":"American medical journal","volume":"7 1","pages":"13-18"},"PeriodicalIF":0.0000,"publicationDate":"2016-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3844/AMJSP.2016.13.18","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American medical journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3844/AMJSP.2016.13.18","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
This retrospective analysis was to study the prevalence of Sexually Transmitted Diseases (STD) in a Reproductive Medical Center in Hong Kong. A total of 1190 patients were included in this study. Group 1A, couples had no symptoms but presented with subinfertility; Group 1B, the subfertile couples were positive for either Chlamydia trachomatis (CT) or Ureaplasma urealyticum (UU); Group 2, couples with symptoms were offered full STD screening including CT, UU, Mycoplasma hominis (MH), Neisseria gonorrhoea (NG), Syphilis, Herpes Simplex Virus 1 and 2. The methods of ELISA and quantitative real-time PCR were used for these analyses. Group 1A: UU detection rates in both male and female (13.84 v.s. 37.07%) were significantly higher than that of CT (5.65 v.s. 5.57%); Group 1B and Group 2: For those who had Full STD check, UU and MH detection rates were significantly higher than that of CT (35, 13.7 and 7.1% respectively). Over 47% of patients showed positive for one or more organism. In the subfertile couples, the UU and CT detection rates were much higher in females than those in males. Both semen and urine samples gave the same rates of infection among CT, UU, NG and MH. U. urealyticum infection rate rather than Chlamydis trachomatis infection is highest in Hong Kong. The infection rate in females is higher than in males. The detection rates in semen and urine samples in males are similar.
本研究旨在回顾性分析香港某生殖医疗中心性传播疾病(STD)的流行情况。本研究共纳入1190例患者。1A组夫妇无症状但表现为亚不孕症;1B组,不育夫妇沙眼衣原体(CT)或解脲支原体(UU)阳性;第2组,有症状的夫妇进行全面性病筛查,包括CT、UU、人支原体(MH)、淋病奈瑟菌(NG)、梅毒、单纯疱疹病毒1型和2型。采用酶联免疫吸附试验(ELISA)和实时荧光定量PCR方法进行分析。1A组:男女UU检出率(13.84 vs . 37.07%)均显著高于CT (5.65 vs . 5.57%);1B组和2组:行STD全检者UU和MH检出率明显高于CT(分别为35.7%、13.7%和7.1%)。超过47%的患者对一种或多种微生物呈阳性。在不育夫妇中,女性UU和CT检出率明显高于男性。在精液和尿液样本中,CT、UU、NG和MH的感染率相同。香港的unrealyticum感染率最高,而沙眼衣原体感染率最高。女性的感染率高于男性。男性精液和尿液样本的检出率相似。