Effect of harvesting age and drying condition on andrographolide content, antioxidant capacity, and antibacterial activity in Andrographis paniculata (Burm.f.) Nees

IF 1.9 Q2 AGRICULTURE, MULTIDISCIPLINARY
H. Chokthaweepanich, Chuleeporn Chumnanka, Sribud Srichaijaroonpong, Rungnapa Boonpawa
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引用次数: 0

Abstract

Quality of dried Andrographis paniculata (Burm.f.) Nees materials is important to determine its effectiveness in traditional medicine. The present study aimed to investigate an effect of harvesting age and drying condition on andrographolide content and its consequences on antioxidant and antibacterial activities. The plants were cultivated and harvested at 90,100,115, and 127 days after sowing (DAS) prior to drying under the sun or using hot air oven at 50, 65, and 80 ℃. The results indicated that drying condition significantly influenced andrographolide content, antioxidant capacities, and antibacterial activity of A. paniculata, whereas the harvesting age had no significant impact on those parameters. The andrographolide contents ranged from 0.74–4.11% (w/w) dry weight. The highest andrographolide contents were obtained at 90 DAS/65 ℃, 127 DAS/65 ℃, and 127 DAS/65 ℃. A. paniculata extracts were found to exhibit antibacterial activity against gram-positive bacterial strains (B. cereus, M. luteus, S. epidermidis, and S. aureus), which the highest antibacterial activity was observed at 90 DAS/65℃. The used of hot air oven at 65 ℃ effectively preserved andrographolide content and antibacterial activity of A. paniculata. In contrast, drying at 50 ℃ was the preferable drying condition for antioxidant capacity. The antioxidant activities of A. paniculata extracts ranged from 3.43–26.73 and 1.93–17.28 mg Trolox/g dry weight for DPPH• scavenging activity and FRAP reducing power activity, respectively. Overall, A. paniculata is suggested to dry using hot air oven at 65 ℃ to maintain high levels of andrograhpolide and antibacterial activity. Drying using hot air oven at 50 ℃ is advised, if antioxidant activity is the main focus. Even though the harvesting age is not a key parameter, A. paniculata is suggested to harvest at 50% flowering stage onward for a better total herbage and andrographolide yield.

采收年龄和干燥条件对穿心莲中穿心莲内酯含量、抗氧化能力和抗菌活性的影响需要雇
干燥穿心莲(缅甸)的品质需要的材料对确定其在传统医学中的有效性很重要。本研究旨在探讨采收年龄和干燥条件对穿心莲内酯含量的影响及其对抗氧化和抗菌活性的影响。在播种后90,100,115和127天(DAS)进行栽培和收获,然后在50,65和80℃的太阳下或热风烘箱下干燥。结果表明,干燥条件对穿心莲内酯含量、抗氧化能力和抗菌活性有显著影响,采收年龄对穿心莲内酯含量、抗氧化能力和抗菌活性无显著影响。穿心莲内酯含量为0.74 ~ 4.11% (w/w)。在90 DAS/65℃、127 DAS/65℃和127 DAS/65℃时,穿心莲内酯含量最高。对革兰氏阳性菌株(蜡样芽孢杆菌、黄体芽孢杆菌、表皮葡萄球菌和金黄色葡萄球菌)的抑菌活性进行了研究,其中在90 DAS/65℃时抑菌活性最高。65℃热风烘箱有效地保存了穿心莲内酯的含量和抗菌活性。相反,在50℃的干燥条件下,抗氧化能力较好。对DPPH•的清除活性为3.43 ~ 26.73 mg,对FRAP的还原活性为1.93 ~ 17.28 mg /g干重。综上所述,建议将穿心莲用热风箱在65℃下干燥,以保持较高的穿心莲内酯含量和抗菌活性。如果主要关注抗氧化活性,建议使用50℃的热风烘箱干燥。尽管采收年龄不是关键参数,但建议在花期50%以后采收,以获得更好的牧草总产量和穿心莲内酯产量。
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来源期刊
AIMS Agriculture and Food
AIMS Agriculture and Food AGRICULTURE, MULTIDISCIPLINARY-
CiteScore
3.70
自引率
0.00%
发文量
34
审稿时长
8 weeks
期刊介绍: AIMS Agriculture and Food covers a broad array of topics pertaining to agriculture and food, including, but not limited to:  Agricultural and food production and utilization  Food science and technology  Agricultural and food engineering  Food chemistry and biochemistry  Food materials  Physico-chemical, structural and functional properties of agricultural and food products  Agriculture and the environment  Biorefineries in agricultural and food systems  Food security and novel alternative food sources  Traceability and regional origin of agricultural and food products  Authentication of food and agricultural products  Food safety and food microbiology  Waste reduction in agriculture and food production and processing  Animal science, aquaculture, husbandry and veterinary medicine  Resources utilization and sustainability in food and agricultural production and processing  Horticulture and plant science  Agricultural economics.
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