Visible Light Promoted One-Pot, Three Component Reaction for the Synthesis of quinazolines

Parshuram Mp, Vinod Tk, R. V, Pradip Bg
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Abstract

Highly efficient one-pot three component approach was developed for the synthesis of biological active quinazoline derivatives. By the application of visible light via SP3 C-H bond activation, desired products were obtained in high yields. The advantages of this method are application of green chemistry approach, avoidance of toxic organic solvents, easily available starting material, simple operation and shorter reaction times.
可见光促进一锅三组分反应合成喹唑啉类化合物
建立了一锅三组分高效合成具有生物活性的喹唑啉衍生物的方法。通过可见光活化SP3碳氢键,得到了高收率的理想产物。该方法的优点是采用绿色化学方法,避免了有毒的有机溶剂,原料容易获得,操作简单,反应时间短。
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