The interaction between 2019-nCoV and interferon I

Q4 Medicine

中华临床感染病杂志 Pub Date : 2021-01-01 DOI:10.3760/cma.j.issn.1674-2397.2021.02.004

J. Guan, Z. Chen, H. Zhu

引用次数: 0

Abstract

COVID-19 has swept across the world, causing widespread epidemics and millions of life lost worldwide. After infected with 2019-nCoV, the body quickly mobilizes the innate immune response and produces type Ⅰ interferon (IFN-Ⅰ). IFN-Ⅰ plays an important role in virus clearance in the early stage of disease. This article reviews the innate immune recognition after virus infection and the interaction between 2019-nCoV and IFN-Ⅰ, which would be conductive to understanding the pathogenesis and antiviral treatment of COVID-19. © 2021 Chinese Medical Association

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来源期刊

中华临床感染病杂志 Medicine-Infectious Diseases

CiteScore

0.70

自引率

0.00%

发文量

1445

期刊介绍： Chinese Journal of Clinical Infectious Diseases started its publication in April 2008. It had been indexed by CSTPCD of Institute of Scientific and Technical Information of China(ISTIC), Chinese Science Citation Database (CSCD), American Chemical Abstract (CA),Western Pacific Region Index Medicus(WPRIM), CNKI, Wanfang Data, Statistical Journal of China Academic Journal Impact Factor Annual Report，etc. The highest impact factor was 1.359, and the comprehensive quality of the journal ranked second in the field of infectious diseases in 2017. The article has been selected as one hundred excellent papers of Chinese medicine in 2018 and 2020, respectively. The journal is available both in print and online.