Pathological Effects of Cypermethrin on the Testes and Accessory Sexual Glands of Yankasa Rams

Abstract

An investigation into the pathological lesions of Cypermethrin on the testes, accessory sexual and pituitary glands of Yankasa rams was carried out. Sixteen Yankasa rams aged 18 30 months and weighing between 21.5 46.5kg were used. The 16 rams were divided equally into two groups (A and B) A served as the treatment group while B served as the control. Group (A) were given Cypermethrin (3%) at the dose rate of 3mg/kg (0.1ml/kg) body weight, topically. Group (B) rams were given distilled water at the same dose rate and route. These treatments were repeated every two weeks for a period of 12 weeks. The rams were sacrifi ced at the end of 12 weeks and the following organs (testes, pituitary, vesicular and prostate glands), were collected and weighed, gross pathological lesions were observed and photographs were taken. The samples were kept for histopathology. Results showed that there were no gross pathological lesions found on the testes, pituitary, prostate glands and the seminal vesicles of both groups. The mean weight of the pituitary gland, the prostate glands and the seminal vesicles of the treated and control groups were statistically not signifi cant (P>0.05). No histologic lesions were found on them. The mean testicular weights of the treated (143.81±7.71g) and the control (130.43±0.63g) were signifi cantly different (P<0.05). There was a reduced number of spermatozoa in the lumen of the seminiferous tubules of the treated group. It was concluded that Cypermethrin reduced spermatozoa in the lumen of the seminiferous tubules. Research Article Pathological Effects of Cypermethrin on the Testes and Accessory Sexual Glands of Yankasa Rams Ubah Simon1*, Ogwu David1, Rekwot Peter1, Rwuaan Joseph1, Chibuogwu Ijeoma2 and Njoku Celestine3 1Department of Theriogenology and Production, Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria, Nigeria 2Animal Science Department, Faculty of Agriculture, University of Abuja, Abuja, Nigeria 3Department of Veterinary Pathology, Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria, Nigeria *Address for Correspondence: Ubah Simon, Department of Theriogenology and Production, Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria, Nigeria, Tel: +2348036097428; Email: drubah2000@yahoo.com Submitted: 06 June 2018 Approved: 19 June 2018 Published: 20 June 2018 Copyright: 2018 Simon U, et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.