Aminophylline combined with roxithromycin in treatment of bronchiectasis

国际医药卫生导报 Pub Date : 2017-01-01 DOI:10.3760/CMA.J.ISSN.1007-1245.2017.01.024

Li Xu

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Abstract

Objective To study the effect of aminophylline combined with roxithromycin in the treatment of bronchiectasis and its effects on pulmonary function. Methods 84 patients with bronchiectasis treated at our hospital from August, 2013 to December, 2015 were randomly divided into a control group and an experimental group, 42 cases for each group. The control group were treated with roxithromycin and the experimental group aminophylline and roxithromycin. The therapeutic effects and the changes of pulmonary function indexes were compared between these two groups before and after treatment. Results After treatment, the PEF, FEV1, and FVC were improved in both groups, but less in the control group than in the experimental group, with statistical differences (P<0.05). The treatment efficacy was lower in the control group than in the experimental group (76.2% vs. 92.9%), with a statistical difference (P<0.05). Conclusions Aminophylline combined with roxithromycin in the treatment of bronchiectasis is significantly effective and can improve lung function and the quality of life. Key words: Aminophylline; Roxithromycin; Bronchiectasis; Curative effect; Lung function improvement

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氨茶碱联合罗红霉素治疗支气管扩张症

目的探讨氨茶碱联合罗红霉素治疗支气管扩张症的疗效及对肺功能的影响。方法将2013年8月~ 2015年12月在我院收治的84例支气管扩张患者随机分为对照组和实验组，每组42例。对照组给予罗红霉素治疗，试验组给予氨茶碱加罗红霉素治疗。比较两组治疗前后的疗效及肺功能指标的变化。结果治疗后，两组患者PEF、FEV1、FVC均有改善，但对照组低于实验组，差异有统计学意义(P<0.05)。对照组治疗疗效低于实验组(76.2% vs. 92.9%)，差异有统计学意义(P<0.05)。结论氨茶碱联合罗红霉素治疗支气管扩张症疗效显著，可改善肺功能和生活质量。关键词:氨茶碱;罗;支气管扩张;疗效;肺功能改善

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国际医药卫生导报

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