Four-dimensional color Doppler ultrasound in examination in prenatal screening of fetal malformation

Abstract

Objective To investigate the diagnostic value of four-dimensional (4D) color Doppler ultrasound examination in prenatal screening of fetal malformation.Methods 1200 pregnant women were observed and detected by four-dimensional color Doppler and two dimensional ultrasound.The results were compared with the results confirmed by clinical pathology.Results 34 cases were detected with congenital defects; among which,10 got defects in nervous system,8 heart deformity,7 cheilopalatognathus,3 urinary tract malformation,3 limb deformity,1 abdominal deformity,and the other 2 cases.31 cases were detected with deformity by four-dimensional color Doppler,with a postpartum coincidence rate of 91.17％; and 3 cases were misdiagnosed,of which 1 case had polydactyly deformity and 2 cases spina bifida.26 cases were detected with deformity by two-dimensional ultrasony,with a postpartum coincidence rate of 76.47％; and 8 cases were misdiagnosed,of which 2 cases had cleft lip and palate,2 case polydactyly deformity,3 cases spina bifida,and 1 cases strephenopodia.There were statistical differences between the two methods (P ＜ 0.05).Conclusions Four-dimensional color Doppler can multi-dimensionally and multi-sectionly observe the abnormal development of fetus and has high clinical value for surface deformity fetus and a more intuitive and accurate judgment. Key words: Four-dimensional color Doppler ultrasound;  Fetus;  Congenital malformation