Inhaling different doses of budesonide for acute asthma attack in children

Abstract

Objective To investigate the clinical effect atomizedly inhaling different doses of budesonide for acute asthma attack in children.Methods 150 children acutely attacked by asthma and admitted into our hospital from March,2012 to March,2014 were randomly divided into a control group,atomizedly inhaling low dose of budesonide,and an observation group,atomizedly inhaling high dose of budesonide.The clinical effect of these two groups were comprehensively compared.Results The total effective rate of the observation group(88.00％)was significantly higher than that of the control group(74.67％) (P ＜ 0.05).PEF and FEV1 were statistically higher after than before the treatment in both groups(P ＜ 0.05) and in the observation group than in the control group(P ＜ 0.05).No adverse reaction was observed in both groups.Conclusions Atomizedly inhaling high dose of budesonide for children acutely attacked by asthma is effective and safe. Key words: High dose;  Budesonide;  Atomization inhalation;  Asthma