Analysis of the effect of cervical conization through cervical endoscopy in the treatment of High-grade cervical intraepithelial neoplasia

中国综合临床 Pub Date : 2020-01-01 DOI:10.3760/CMA.J.ISSN.1008-6315.2020.01.002

Jing Guo, Dan Yang, X. Fu, Dongqi Jia

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Abstract

Objective To investigate the clinical effect of cervical conization under cervical endoscopy in high-grade cervical intraepithelial neoplasia (CIN). Methods From June 2017 to June 2019, 100 patients with grade II and III CIN admitted to Harbin First Hospital were divided into control group and observation group with 50 cases in each group by random number table method.The control group was treated with traditional cervical cold knife conization, while the observation group was treated with cervical conization under endoscopy.To compare the therapeutic effects of two surgical methods. Results The incidence of positive margin were significantly lower than that in the control group(8%(4/50) and 18%(9/50)), and the difference was statistically significant (χ2=4.98, P 0.05). Conclusion The cervical conization through cervical canal endoscope can accurately locate the focus of high-grade CIN, with higher rate of lesion clearance, lower rate of lesion recurrence and complications. Key words: Conization of cervix; Endoscopy; Cervical intraepithelial neoplasia

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宫颈内镜下宫颈锥切术治疗高级别宫颈上皮内瘤变的疗效分析

目的探讨宫颈内镜下宫颈锥切术治疗高级别宫颈上皮内瘤变(CIN)的临床效果。方法选取2017年6月~ 2019年6月在哈尔滨市第一医院住院的II、III级CIN患者100例，采用随机数字表法分为对照组和观察组，每组各50例。对照组采用传统颈冷刀锥切术，观察组采用内镜下颈冷刀锥切术。比较两种手术方式的治疗效果。结果阳性切缘发生率显著低于对照组(8%(4/50)、18%(9/50))，差异有统计学意义(χ2=4.98, p0.05)。结论颈管内镜下宫颈锥切术能准确定位高级别CIN病灶，病灶清除率高，复发率低，并发症少。关键词:宫颈锥切术;内窥镜检查;宫颈上皮内瘤变

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来源期刊

中国综合临床

CiteScore

0.10

自引率

0.00%

发文量

16855

期刊介绍： Clinical Medicine of China is an academic journal organized by the Chinese Medical Association (CMA), which mainly publishes original research papers, reviews and commentaries in the field. Clinical Medicine of China is a source journal of Peking University (2000 and 2004 editions), a core journal of Chinese science and technology, an academic journal of RCCSE China Core (Extended Edition), and has been published in Chemical Abstracts of the United States (CA), Abstracts Journal of Russia (AJ), Chinese Core Journals (Selection) Database, Chinese Science and Technology Materials Directory, Wanfang Database, China Academic Journal Database, JST Japan Science and Technology Agency Database (Japanese) (2018) and other databases.