{"title":"Ebola virus and innate immunity","authors":"Jingxi Zhang, Cheng-zhong Li, Chong Bai","doi":"10.3724/SP.J.1008.2015.00607","DOIUrl":null,"url":null,"abstract":"Ebola virus disease(EVD)caused by Ebora virus(EBOV)is one of the most violent infectious disease so far.It is so highly infective and fatal that there has been no effective treatment until now.Ebola viral infection can cause a series of immune responses.Specific and nonspecific antiviral innate immune deficiency in the hosts is a recognized important reason for EVD associated death.This paper reviews the influence of EBOV on innate immune reaction of humans and the corresponding countermeasures.","PeriodicalId":6893,"journal":{"name":"海军军医大学学报","volume":"2 1","pages":"607"},"PeriodicalIF":0.0000,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"海军军医大学学报","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3724/SP.J.1008.2015.00607","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Ebola virus disease(EVD)caused by Ebora virus(EBOV)is one of the most violent infectious disease so far.It is so highly infective and fatal that there has been no effective treatment until now.Ebola viral infection can cause a series of immune responses.Specific and nonspecific antiviral innate immune deficiency in the hosts is a recognized important reason for EVD associated death.This paper reviews the influence of EBOV on innate immune reaction of humans and the corresponding countermeasures.
期刊介绍:
Founded in 1980, Academic Journal of Second Military Medical University(AJSMMU) is sponsored by Second Military Medical University, a well-known medical university in China. AJSMMU is a peer-reviewed biomedical journal,published in Chinese with English abstracts.The journal aims to showcase outstanding research articles from all areas of biology and medicine,including basic medicine(such as biochemistry, microbiology, molecular biology, genetics, etc.),clinical medicine,public health and epidemiology, military medicine,pharmacology and Traditional Chinese Medicine),to publish significant case report, and to provide both perspectives on personal experiences in medicine and reviews of the current state of biology and medicine.