Prostate biopsy guided by transrectal ultrasound combined with MRI compartmental localization in diagnosis of prostate cancer

Q4 Medicine
Hui-qing Wang, Guang’an Xiao, Bo Yang, Guodong Jing, Chao Zhang, F. Guo, Yinghao Sun
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引用次数: 0

Abstract

Objective To explore the value of prostate biopsy guided by transrectal ultrasound combined with MRI compartmental localization in the diagnosis of prostate cancer.Methods Fifty patients with elevated prostate specific antigen levels were recruited in this study.All the patients underwent MRI scan before biopsy and the prostate was divided into 12 compartments accordingly.The direction and region of the division were consistent with the ultrasound.Systematic 12-samples needle biopsy was performed and additional biopsy was done for the suspected compartments.According to histopathology,the positive detection rates of systematic 12-samples needle biopsy and systematic biopsy combined with added punctures of suspected compartments were analyzed and compared.Results Prostate cancer detection rate of systematic biopsy combined with punctures of suspected compartment was significantly higher than that of systematic 12-samples needle biopsy(42.0% vs 36.0%,P 0.05).Systematic biopsy combined with punctures of suspected compartment caused hematuria in 5 cases,bloody stools in 13 cases,and fever in one,and there were no other complications.Conclusion Transrectal ultrasound combined with MRI compartmental localization can improve the outcome of prostate biopsy,benefiting the early diagnosis of prostate cancer.
经直肠超声引导下前列腺活检联合MRI隔室定位诊断前列腺癌
目的探讨经直肠超声引导下前列腺活检结合MRI隔室定位对前列腺癌的诊断价值。方法选择前列腺特异性抗原水平升高的患者50例。所有患者活检前均行MRI扫描,并将前列腺划分为12个区室。分裂的方向和区域与超声一致。对12个样本进行了系统的针活检,并对可疑的隔室进行了额外的活检。根据组织病理学,分析比较系统12例穿刺活检与系统活检合并疑似隔室穿刺的阳性检出率。结果系统活检联合可疑间室穿刺前列腺癌检出率显著高于系统12例穿刺前列腺癌检出率(42.0% vs 36.0%,P < 0.05)。系统活检合并疑似隔室穿刺导致血尿5例,血便13例,发热1例,无其他并发症。结论经直肠超声联合MRI隔室定位可提高前列腺活检的预后,有利于前列腺癌的早期诊断。
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来源期刊
海军军医大学学报
海军军医大学学报 Medicine-Medicine (all)
CiteScore
0.50
自引率
0.00%
发文量
14752
期刊介绍: Founded in 1980, Academic Journal of Second Military Medical University(AJSMMU) is sponsored by Second Military Medical University, a well-known medical university in China. AJSMMU is a peer-reviewed biomedical journal,published in Chinese with English abstracts.The journal aims to showcase outstanding research articles from all areas of biology and medicine,including basic medicine(such as biochemistry, microbiology, molecular biology, genetics, etc.),clinical medicine,public health and epidemiology, military medicine,pharmacology and Traditional Chinese Medicine),to publish significant case report, and to provide both perspectives on personal experiences in medicine and reviews of the current state of biology and medicine.
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