Changes In Serum Leptin And Nesfatin-1 Levels Measured Before And After Acupuncture In Overweight/obese Patients: A Randomized Controlled Trial

IF 0.2 4区医学 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE

Acupuncture & Electro-Therapeutics Research Pub Date : 2021-01-01 DOI:10.3727/036012921x16321477053953

Tevhid Aydin, R. Kutlu, H. Alp, I. Kilinç

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引用次数: 0

Abstract

Obesity has become a global epidemic and public health crisis in our country as well as all over the world.We aimed to investigate the changes in serum leptin and nesfatin-1 levels measured before and after acupuncture in overweight/obese patients. This randomized controlled study was carried out on 90 overweight/obese patients. Participants were divided into three groups: Group 1 (Acupuncture), Group 2 (Diet), and Group 3 (Control). Serum leptin and nesfatin-1 levels were measured before and after the intervention. The 30 days leptin values were significantly decreased in the acupuncture group (p=0.040) while they were significantly increased in the control group (p=0.039). It was detected that the nesfatin-1 values were significantly increased in both acupuncture (p=0.032) and diet groups (p=0.017). Also, body weights significantly decreased both in acupuncture (p=0.032) and diet groups (p<0.001). In the present study, auricular acupuncture was found to be more effective than body acupuncture in reducing body weight. Our results support the effects of acupuncture treatment on appetite hormones. Further research on the mechanisms of endogenous and exogenous actions of the recently discovered hormones leptin and nesfatin-1 isneeded.

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超重/肥胖患者针灸前后血清瘦素和Nesfatin-1水平的变化:一项随机对照试验

肥胖已成为一种全球性的流行病和公共卫生危机，在我国乃至全世界都是如此。我们的目的是研究超重/肥胖患者针灸前后血清瘦素和nesfatin-1水平的变化。本研究对90例超重/肥胖患者进行了随机对照研究。参与者被分为三组:1组(针灸)，2组(饮食)和3组(对照组)。测定干预前后血清瘦素和nesfatin-1水平。针刺组30天瘦素值显著降低(p=0.040)，对照组30天瘦素值显著升高(p=0.039)。针刺组(p=0.032)和饮食组(p=0.017)的nesfat -1值均显著升高。此外，针灸组(p=0.032)和饮食组(p<0.001)体重均显著降低。在本研究中，耳针在减轻体重方面比体针更有效。我们的研究结果支持针灸治疗对食欲激素的影响。新近发现的激素瘦素和nesfatin-1的内源性和外源性作用机制有待进一步研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acupuncture & Electro-Therapeutics Research 医学-全科医学与补充医学

CiteScore

0.50

自引率

66.70%

发文量

审稿时长

>12 weeks

期刊介绍： The aim of the journal is to provide an international forum for the exchange of ideas and promotion of basic and clinical research in acupuncture, electro-therapeutics, and related fields. The journal was established in order to make acupuncture and electro-therapeutics a universally acceptable branch of medicine through multidisciplinary research based on scientific disciplines. The final goal is to provide a better understanding of both the beneficial and adverse effects of these treatments in order to supplement or improve existing methods of diagnosis, prognosis, treatment, and prevention of diseases in both Western and Oriental medicine.