Short-term Outcomes of Acupuncture Interventions on Uterine Adenomyosis: ASystematic Review and Meta-analysis

IF 0.2 4区医学 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE

Acupuncture & Electro-Therapeutics Research Pub Date : 2021-01-01 DOI:10.3727/036012921x16304136917573

Qi Li, Yunxia Li, Lu Fan, Su Yuan

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引用次数: 0

Abstract

The purpose of this systematic review is to evaluate for evidence of the association of acupuncture with relieving the symptoms of adenomyosis. We searched ten electronic databases and included randomized controlled trials(RCTs) in women with adenomyosis. The methodological quality was moderate evidence level by Cochrane risk-of-bias criteria. The results were analyzed by Review Manager 5.3 and expressed as standardized mean differences (SMD) or mean differences (MD). Eleven RCTs (942 subjects) were included in this meta-analysis. Analysis with no heterogeneity showed that acupuncture group obtained a significant better effect (95% CI,-0.48 to-0.10; I²= 0%) on reducing the size of the uterus and was superior in the shrink of carbohydrate antigen 125 (CA125) level (95% CI,-1.13 to-0.44; I² =0%) than that in pharmacological medicine alone group. Moreover, acupuncture was significantly associated with improving patients’ dysmenorrheal symptoms after 3-month menstrual cycles treatment (95% CI,-1.09to-0.06).The adverse events, especially the incidence of hot flashes, were less reported in acupuncture group compared to pharmacological medicine alone group (Odds Ratio, OR, 0.17; 95% CI, 0.08 to 0.35;I²= 0%).Acupuncture therapy is a promising avenue for the development of alternatives to surgery and medicine in the treatment of adenomyosis. However, further rigorous trials are needed to confirm the claims of our results.

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针刺干预子宫bbb的短期疗效:系统回顾和meta分析

本系统综述的目的是评估针灸与缓解b子宫腺肌症症状相关的证据。我们检索了10个电子数据库，纳入了随机对照试验(rct)，研究对象为子宫腺肌症女性。按照Cochrane偏倚风险标准，方法学质量为中等证据水平。结果通过Review Manager 5.3进行分析，并以标准化平均差异(SMD)或平均差异(MD)表示。11项随机对照试验(942名受试者)纳入本荟萃分析。无异质性分析显示，针刺组获得了显著更好的效果(95% CI，-0.48 ~ 0.10;I²= 0%)对缩小子宫大小有显著的影响，在碳水化合物抗原125 (CA125)水平的缩小方面优于对照组(95% CI，-1.13 ~ 0.44;I²=0%)，较单用药物组明显增加。此外，针灸与月经周期治疗3个月后患者痛经症状的改善显著相关(95% CI，-1.09 ~ 0.06)。针刺组的不良事件，尤其是潮热的发生率较单独用药组少(优势比OR, 0.17;95% CI, 0.08 ~ 0.35;I²= 0%)。针刺疗法是发展替代手术和药物治疗子宫腺肌症的有前途的途径。然而，需要进一步严格的试验来证实我们的结果。

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来源期刊

Acupuncture & Electro-Therapeutics Research 医学-全科医学与补充医学

CiteScore

0.50

自引率

66.70%

发文量

审稿时长

>12 weeks

期刊介绍： The aim of the journal is to provide an international forum for the exchange of ideas and promotion of basic and clinical research in acupuncture, electro-therapeutics, and related fields. The journal was established in order to make acupuncture and electro-therapeutics a universally acceptable branch of medicine through multidisciplinary research based on scientific disciplines. The final goal is to provide a better understanding of both the beneficial and adverse effects of these treatments in order to supplement or improve existing methods of diagnosis, prognosis, treatment, and prevention of diseases in both Western and Oriental medicine.