Efficacy and Safety of Acupuncture with Western Medicine for Rheumatoid Arthritis: A Systematic Review and Meta-analysis

IF 0.2 4区医学 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE

Acupuncture & Electro-Therapeutics Research Pub Date : 2021-01-01 DOI:10.3727/036012921x16237619666076

Xinhui Huo, L. Liang, Xia Ding, Angshaer Bihazi, Haiyan Xu

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引用次数: 0

Abstract

Objectives: In the present study, we assessed the therapeutic qualities of the combination of acupuncture with Western medicine to determine further lines of clinical research. Methods: We searched English-language databases and Chinese-language databases for randomized controlled trials (RCTs) published up to February 2020. Two reviewers performed a meta-analysis of the efficacy and toxicity of the use of acupuncture with Western medicine for RA measured by a visual analogue scale (VAS), rheumatoid factor (RF), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP). Results: In total, 9 RCTs involving 698 patients were included for analysis. VAS, ESR, CRP, and RF were all shown to favor the combination of acupuncture with Western medicine compared to Western medicine alone. ST36 (Zusanli), EX-UE9 (Baxie), Ll11 (Quchi), GB34 (Yanglingquan), TE14 (Jianliao) and TE4(Yangchi) were frequently used in 9 clinical trials. Conclusion: Treatment using acupuncture with Western medicine was associated with higher efficacy and lower risks than treatment with Western medicine alone. ST36 (Zusanli), EX-UE9 (Baxie), Ll11 (Quchi), GB34 (Yanglingquan), TE14 (Jianliao) and TE4 (Yangchi) were frequently used in treatment of RA and had been verified with effect in clinical practice.

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西药针刺治疗类风湿关节炎的疗效和安全性:系统综述和荟萃分析

目的:在本研究中，我们评估了针灸与西药结合的治疗质量，以确定进一步的临床研究方向。方法:我们检索了截至2020年2月发表的英文数据库和中文数据库中的随机对照试验(rct)。两名评论者通过视觉模拟量表(VAS)、类风湿因子(RF)、红细胞沉降率(ESR)和c反应蛋白(CRP)对针灸结合西药治疗RA的疗效和毒性进行了荟萃分析。结果:共纳入9项rct, 698例患者。VAS、ESR、CRP、RF均显示针刺与西药联合优于单用西药。ST36(足三里)、EX-UE9(百泻)、Ll11(曲池)、GB34(阳陵泉)、TE14(健辽)和TE4(阳池)在9项临床试验中被频繁使用。结论:西医结合针灸治疗比单纯西医治疗疗效高、风险低。ST36(足三里)、EX-UE9(百邪)、Ll11(曲池)、GB34(阳陵泉)、TE14(健脾)、TE4(阳池)是治疗RA常用的药物，临床已证实疗效良好。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acupuncture & Electro-Therapeutics Research 医学-全科医学与补充医学

CiteScore

0.50

自引率

66.70%

发文量

审稿时长

>12 weeks

期刊介绍： The aim of the journal is to provide an international forum for the exchange of ideas and promotion of basic and clinical research in acupuncture, electro-therapeutics, and related fields. The journal was established in order to make acupuncture and electro-therapeutics a universally acceptable branch of medicine through multidisciplinary research based on scientific disciplines. The final goal is to provide a better understanding of both the beneficial and adverse effects of these treatments in order to supplement or improve existing methods of diagnosis, prognosis, treatment, and prevention of diseases in both Western and Oriental medicine.