Early Predictors of Delayed Respiratory Failure after Glufosinate Ammonium Ingestion

IF 0.4 4区医学 Q4 PHARMACOLOGY & PHARMACY

Indian Journal of Pharmaceutical Sciences Pub Date : 2023-01-01 DOI:10.36468/pharmaceutical-sciences.spl.677

MU H.W., P. Hsieh, Sheng Pang Hsiao, C. H. Chen, Kai Wei Yang, C. Pan, H. Shih, F. Huang, D. Hung

引用次数: 0

Abstract

Acute glufosinate ammonium poisoning can cause neurological complications and respiratory failure, which are usually delayed and difficult to predict. Serum ammonia level might be an indicator of severe glufosinate poisoning, but it has not been confirmed. We aimed to investigate the potential predictors of respiratory failure after glufosinate poisoning. We conducted a retrospective review of 21 cases of glufosinate poisoning between 2010 and 2019. Patients were assigned to intubated due to respiratory failure and non-intubated groups. The following characteristics were compared between these two groups; age, sex and period from poisoning to hospital arrival, vital signs, Glasgow coma scale, laboratory parameters and electrocardiogram measurements. Furthermore, the outcomes of morbidity and mortality were analyzed. Totally, 12 cases were be intubated and the other 9 were not intubated.

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草甘膦铵摄入后迟发性呼吸衰竭的早期预测因素

急性草铵膦中毒可引起神经系统并发症和呼吸衰竭，通常是延迟的，难以预测。血清氨水平可能是草甘膦严重中毒的一个指标，但尚未得到证实。我们的目的是研究草甘膦中毒后呼吸衰竭的潜在预测因素。我们对2010年至2019年间21例草铵膦中毒进行了回顾性分析。患者被分为呼吸衰竭插管组和非插管组。比较两组患者的以下特征:年龄，性别和中毒到医院的时间，生命体征，格拉斯哥昏迷量表，实验室参数和心电图测量。此外，还分析了发病率和死亡率的结果。12例插管，9例未插管。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian Journal of Pharmaceutical Sciences PHARMACOLOGY & PHARMACY-

自引率

0.00%

发文量

审稿时长

2 months

期刊介绍： The Indian Journal of Pharmaceutical Sciences (IJPS) is a bi-monthly Journal, which publishes original research work that contributes significantly to further the scientific knowledge in Pharmaceutical Sciences (Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy and Phytochemistry, Pharmacology and Therapeutics, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Pharmacovigilance, Pharmacoepidemiology, Pharmacoeconomics, Drug Information, Patient Counselling, Adverse Drug Reactions Monitoring, Medication Errors, Medication Optimization, Medication Therapy Management, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest). The Journal publishes original research work either as a Full Research Paper or as a Short Communication. Review Articles on current topics in Pharmaceutical Sciences are also considered for publication by the Journal.