Post Treatment Complication of Enteric Fever: A Rare Presentation

N. Paul, R. Islam, N. Nusrat, F. Rahman, M. Hasan
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Abstract

Background: Enteric fever is one of the common infectious diseases worldwide. Ceftriaxone is the most commonly used sensitive antibiotic for enteric fever. Biliary sludge is an important complication of ceftriaxone. Biliary sludge refers to a viscous mixture of small particles derived from bile. These sediments consist of cholesterol crystals, calcium salts, calcium bilirubinate, mucin, and other materials. For patients without symptoms, no treatment is recommended. If patients become symptomatic and/or develop complications, cholecystectomy is indicated. This is case report of a 9 year old boy diagnosed as a case of enteric fever and treated with appropriate dose of ceftriaxone for 8 days. On the day of discharge, at night the boy developed severe abdominal pain. They took surgical consultation; ultrasonography of whole abdomen was done which revealed multiple calculi in gall bladder. Symptomatic treatment was planned followed by surgical removal of biliary calculi. After 20 days they took surgical consultation again. Surgeon was ready to perform surgery. The worried mother requested for repeat USG of whole abdomen and this time finding was normal. We must be aware about side effects of ceftriaxone. Patients should be followed up after completion of treatmentand as biliary sludge is often self-limiting and surgery is not required for all cases. Delta Med Col J. Jul 2016 4(2): 97-100
肠热治疗后并发症:罕见的表现
背景:肠热是世界范围内常见的传染病之一。头孢曲松是治疗肠热最常用的敏感抗生素。胆道淤渣是头孢曲松治疗的重要并发症。胆泥是指胆汁中产生的小颗粒的粘稠混合物。这些沉积物由胆固醇晶体、钙盐、胆红素钙、粘蛋白和其他物质组成。对于无症状的患者,不建议治疗。如果患者出现症状和/或出现并发症,则需要胆囊切除术。这是一个9岁男孩的病例报告,诊断为肠热病病例,并给予适当剂量的头孢曲松治疗8天。出院当天晚上,男孩出现了严重的腹痛。他们接受外科会诊;全腹超声检查发现胆囊多发结石。计划对症治疗,然后手术切除胆结石。20天后,他们再次接受外科会诊。外科医生准备做手术。担心的母亲要求再次做全腹超声心动图,这次结果正常。我们必须注意头孢曲松的副作用。患者应在治疗完成后进行随访,因为胆道淤渣通常是自限性的,并非所有病例都需要手术。中华医学杂志,2016,34 (2):97-100
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