An investigation into fatigue post-stroke and its multidimensional nature

Abstract

Abstract There is increasing anecdotal and scientific evidence of the presence of fatigue following stroke. This study examines this fatigue and evaluates the relationship between fatigue and other factors post-stroke, such as physical function, depression and reintegration to normal living. A cross-sectional case–control methodology was used. People with stroke were recruited from two day hospitals, Volunteer Stroke Scheme meetings and active retirement groups. Control subjects were recruited from active retirement groups in the same catchment area. One hundred people with stroke and 100 age- and gender-matched controls completed four standardized outcome measures: the Multidimensional Fatigue Inventory, Geriatric Depression Scale, Barthel Index and Reintegration to Normal Living Index. Demographic details were also recorded. Fatigue levels are significantly higher in people who have had a stroke. No relationship was demonstrated between fatigue and physical function or reintegration to normal living. Fatigue and depression co-existed in many respondents; however, fatigue was also seen to be independent of depression. Depression did not have an effect on fatigue in people with stroke. Fatigue needs to be considered in the rehabilitation process post-stroke. It is independent of depression and may persist up to 3 years post-stroke.