The Correlation between Hyperuricemia and Cardiovascular Morbidities among Hemodialysis Patients Attending the Academy Charity Teaching Hospital From Jan 2019 - Dec 2019

Cardiology and cardiovascular medicine Pub Date : 2022-01-01 DOI:10.26502/fccm.92920276

Mohammed Walid Khalil Abushunnar

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引用次数: 1

Abstract

Background: Little is known about the role of serum uric acid in cardiovascular events with no specific data on the relationship between hyperuricemia and cardiovascular morbidities in the chronic hemodialysis setting. Objectives: To determine The prevalence of hyperuricemia and the association between uric acid level and various cardiovascular morbidities in patients with ESRF whom undergoing regular hemodialysis sessions. Methods: Descriptive retrospective facility based study included all hemodialysis patients who attended the hemodialysis unit at the Academy Charity Teaching Hospital from January 2019 – December 2019 which was equivalent to 150 patients, Data collected from patient’s files using data collection sheet then entered in Microsoft-excel and analyzed statistically using SPSS. Results: the study population included 150 patients, Male to female ratio 3:2, with a mean age of 54 years ±17. (21.3%) of the study participants live in Jabra region, 57% were jobless (30% were unemployed and 27% were housewives). CKD represented 89,59% of the etiological factors of ESRF. The median time spent by patients since the start of dialysis is 36 months. The overall prevalence of hyperuricemia was 62% and The most frequently associated comorbid condition was hypertension with 99% followed by Myocardial Infarction with 12.7% of patients. 44% of participants were taking Allopurinol plus CaCo3 and 18% were CaCo3 alone. the association between the serum uric acid levels and myocardial infarction was proven to be statistically significant with p value of 0.037. On the other hand, association between hyperuricemia and stroke, heart failure was found to be statistically insignificant. Conclusion: prevalence of hyperuricemia is high in patients with ESRD whom undergoing regular hemodialysis sessions and Serum uric acid is significantly associated with myocardial infarction. Hyperuricemia should be acknowledged and monitored as a risk factor for cardiovascular disease.

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2019年1月- 2019年12月我院慈善教学医院血液透析患者高尿酸血症与心血管疾病的相关性研究

背景:我们对血清尿酸在心血管事件中的作用知之甚少，也没有关于慢性血液透析患者高尿酸血症与心血管疾病之间关系的具体数据。目的:确定接受定期血液透析的ESRF患者高尿酸血症的患病率以及尿酸水平与各种心血管疾病之间的关系。方法:基于描述性回顾性设施的研究纳入了2019年1月- 2019年12月在学院慈善教学医院血透病房就诊的所有血液透析患者，相当于150例患者，使用数据收集表从患者档案中收集数据，然后在Microsoft-excel中输入数据，使用SPSS进行统计分析。结果:纳入研究人群150例，男女比例3:2，平均年龄54岁±17岁。(21.3%)的研究参与者居住在Jabra地区，57%的人失业(30%的人失业，27%的人是家庭主妇)。CKD占ESRF病因的89.59%。患者从透析开始的中位时间为36个月。高尿酸血症的总体患病率为62%，最常见的合并症是高血压(99%)，其次是心肌梗死(12.7%)。44%的参与者服用别嘌呤醇加CaCo3, 18%的参与者单独服用CaCo3。血清尿酸水平与心肌梗死的相关性有统计学意义，p值为0.037。另一方面，高尿酸血症与中风、心力衰竭之间的关联在统计上不显著。结论:高尿酸血症在定期进行血液透析的ESRD患者中患病率高，血清尿酸与心肌梗死显著相关。高尿酸血症应被视为心血管疾病的危险因素并加以监测。

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Cardiology and cardiovascular medicine

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