O. M. Awad, S. El-Fiki, R. Abou-Shanab, N. Hassanin, R. A. Rahman
{"title":"Influence of exposure to pesticides on liver enzymes and cholinesterase levels in male agriculture workers","authors":"O. M. Awad, S. El-Fiki, R. Abou-Shanab, N. Hassanin, R. A. Rahman","doi":"10.30955/GNJ.001285","DOIUrl":null,"url":null,"abstract":"A significant increase in pesticide use has increased concerns about potentially adverse effects on human health and the environment. The study aimed to explore the effects of exposure to pesticides on the liver function and acetycholinesterase levels in serum (AChES) and red blood cells (AChER) of 100 male participating in agricultural work ranging in age between 20 and 60 year with mean age 37.11±9.3. One hundred males matched for age and socio economic status were recruited as a control group to compare levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), bilriubin, alkaline phosphatase (ALP), total protein, AChES and AChER. The results indicate that AST, ALT and ALP were significantly (P<0.05) increased in pesticide-exposed workers compared with control. There was also a highly significantly (P<0.01) decrease in AChER among male agriculture workers compared with controls. At 10 50 times of pesticides applications there was a significantly (P<0.05) decrease in AChER and increase in AST, ALT and ALP activity among exposed group. However, there was a negative correlation between AST, ALT, direct bilirubin, and AChES and age among control group and a positive correlation between ALT and AST and age among exposed group. According to the number of pesticide application, there was a positive correlation between AST, ALP, total and direct bilirubin and number of pesticide application. Agricultural villages in Egypt require more attention to decrease the percentage of literacy among the farmers and raise their health awareness.","PeriodicalId":55087,"journal":{"name":"Global Nest Journal","volume":"16 1","pages":"1006-1015"},"PeriodicalIF":1.2000,"publicationDate":"2014-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"24","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Global Nest Journal","FirstCategoryId":"93","ListUrlMain":"https://doi.org/10.30955/GNJ.001285","RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}
引用次数: 24
Abstract
A significant increase in pesticide use has increased concerns about potentially adverse effects on human health and the environment. The study aimed to explore the effects of exposure to pesticides on the liver function and acetycholinesterase levels in serum (AChES) and red blood cells (AChER) of 100 male participating in agricultural work ranging in age between 20 and 60 year with mean age 37.11±9.3. One hundred males matched for age and socio economic status were recruited as a control group to compare levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), bilriubin, alkaline phosphatase (ALP), total protein, AChES and AChER. The results indicate that AST, ALT and ALP were significantly (P<0.05) increased in pesticide-exposed workers compared with control. There was also a highly significantly (P<0.01) decrease in AChER among male agriculture workers compared with controls. At 10 50 times of pesticides applications there was a significantly (P<0.05) decrease in AChER and increase in AST, ALT and ALP activity among exposed group. However, there was a negative correlation between AST, ALT, direct bilirubin, and AChES and age among control group and a positive correlation between ALT and AST and age among exposed group. According to the number of pesticide application, there was a positive correlation between AST, ALP, total and direct bilirubin and number of pesticide application. Agricultural villages in Egypt require more attention to decrease the percentage of literacy among the farmers and raise their health awareness.
期刊介绍:
Global Network of Environmental Science and Technology Journal (Global NEST Journal) is a scientific source of information for professionals in a wide range of environmental disciplines. The Journal is published both in print and online.
Global NEST Journal constitutes an international effort of scientists, technologists, engineers and other interested groups involved in all scientific and technological aspects of the environment, as well, as in application techniques aiming at the development of sustainable solutions. Its main target is to support and assist the dissemination of information regarding the most contemporary methods for improving quality of life through the development and application of technologies and policies friendly to the environment