Collagen and Keratin as a Components of Hydrogels

IF 0.7 4区 工程技术 Q3 MATERIALS SCIENCE, TEXTILES
D. Wieczorek, Anna Słubik, Iwona Masłowska-Lipowicz, D. Gendaszewska, K. Ławińska
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引用次数: 1

Abstract

Abstract Smart hydrogels, or stimuli-responsive hydrogels, can and should play an important role as excellent drug carriers. These three-dimensional structure materials are composed of crosslinked hydrophilic polymer chains that are able to dramatically change their volume and other properties in response to environmental stimuli, such as pH, temperature and solvent changes. The main goal of individual research projects was the development of new hydrogels based on polypeptides. These hybrid materials are crosslinked hydrophilic polymers capable of absorbing large amounts of water, saline or physiological solutions. Superabsorbent hydrogels based on natural materials are non-toxic, biocompatible and biodegradable. Unfortunately, their mechanical properties in the swollen state are weak. In this article, we present a review of literature on the synthesis of smart hydrogels based on keratin or collagen with synthetic materials.
胶原蛋白和角蛋白是水凝胶的组成成分
摘要智能水凝胶,即刺激反应性水凝胶,可以而且应该作为优良的药物载体发挥重要作用。这些三维结构材料由交联的亲水性聚合物链组成,能够根据环境刺激(如pH值、温度和溶剂变化)显著改变其体积和其他性能。个别研究项目的主要目标是开发基于多肽的新型水凝胶。这些杂化材料是交联的亲水性聚合物,能够吸收大量的水、生理盐水或生理溶液。基于天然材料的高吸水性水凝胶无毒,具有生物相容性和可生物降解性。不幸的是,它们在膨胀状态下的力学性能很弱。本文综述了以角蛋白或胶原蛋白为原料合成智能水凝胶的研究进展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Fibres & Textiles in Eastern Europe
Fibres & Textiles in Eastern Europe 工程技术-材料科学:纺织
CiteScore
1.60
自引率
11.10%
发文量
12
审稿时长
13.5 months
期刊介绍: FIBRES & TEXTILES in Eastern Europe is a peer reviewed bimonthly scientific journal devoted to current problems of fibre, textile and fibrous products’ science as well as general economic problems of textile industry worldwide. The content of the journal is available online as free open access. FIBRES & TEXTILES in Eastern Europe constitutes a forum for the exchange of information and the establishment of mutual contact for cooperation between scientific centres, as well as between science and industry.
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