A DESCRIPTIVE STUDY OF EPILEPTIC PATIENTS IN HERAT CITY OF AFGHANISTAN

A. Haidery, R. Kakar
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Abstract

Epilepsy is one of the most common and serious neurological disorders which is characterized by recurrent unprovoked seizures. Its prevalence ranges from 0.5% to 1% of the population in developed countries, and even higher in developing countries. Around 70 million people worldwide have epilepsy. This research aims to perform a descriptive study on epileptic children 7-18 years old in Herat city of Afghanistan.This descriptive study was performed on 7-18 years old children with epilepsy, which was conducted from in 2021 in Herat city of Afghanistan. The study included 100 patients with epileptic disorders, in this study Encephalography, Magnetic resonance imaging, Computed tomography, and Sociodemographic information were used to describe the patients. The main group of this study included 100 epileptic children. The age of study participants ranged from 7-18 years and the mean age was 9.21 ± 2.64 years. 46 (51.1%) were males and 44 (48.9%) were females. More often Epilepsy cases were observed in patients with focal seizures. Hereditary predisposition was found as a risk factor and it was statistically significant, the p-value was less than 0.0007. Having status epilepsy was also found a risk factor for epilepsy and the p-value was 0.001. Also, prognostic factors for refractory epilepsy were determined in this study. The risk factors that were found in epileptic patients, were high and comparable with other studies in the world literature. More often epilepsy cases were determined in patients with focal seizures, hereditary predisposition, and having status epilepsy also found as prevalent risk factors for refractory epilepsy. Also, prognostic factors for epilepsy were identified. Negative factors were a high number of seizures, abnormal electroencephalography findings, and early onset of seizures in epileptic patients.
阿富汗赫拉特市癫痫患者的描述性研究
癫痫是最常见和最严重的神经系统疾病之一,其特征是复发性无端发作。其患病率在发达国家占人口的0.5%至1%,在发展中国家甚至更高。全世界约有7000万人患有癫痫。本研究旨在对阿富汗赫拉特市7-18岁癫痫儿童进行描述性研究。本描述性研究于2021年在阿富汗赫拉特市对7-18岁癫痫患儿进行。本研究纳入100例癫痫性疾病患者,采用脑电图、磁共振成像、计算机断层扫描和社会人口学信息对患者进行描述。本研究的主要对象为100例癫痫患儿。研究对象年龄7 ~ 18岁,平均年龄9.21±2.64岁。男性46例(51.1%),女性44例(48.9%)。癫痫多见于局灶性发作患者。遗传易感性为危险因素,p值< 0.0007,差异有统计学意义。癫痫状态也被发现是癫痫的危险因素,p值为0.001。此外,本研究还确定了难治性癫痫的预后因素。在癫痫患者中发现的危险因素很高,与世界文献中的其他研究相当。更常见的癫痫病例确定为局灶性癫痫,遗传易感性和状态癫痫也被认为是难治性癫痫的普遍危险因素。此外,癫痫的预后因素也被确定。负面因素为癫痫患者癫痫发作次数高、脑电图异常、癫痫发作早。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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