Ondrea A. Moore, Ying Gao, Allen Y. Chen, Ross Brittain, Y. Chen
{"title":"The Extraction, Anticancer Effect, Bioavailability, and Nanotechnology of Baicalin","authors":"Ondrea A. Moore, Ying Gao, Allen Y. Chen, Ross Brittain, Y. Chen","doi":"10.23937/2572-3278.1510011","DOIUrl":null,"url":null,"abstract":"The dried root of Baikal skullcap (Scutellaria baicalensis) has been historically and widely used in traditional Eastern medicine. Modern science proved that baicalin is the major bioactive responsible for the physiological activity of Baikal skullcap. Baicalin, a flavonoid found in several species in the genus Scutellaria, has been regarded as a potent anticancer agent. In this review, we present the main extraction methods, anticancer activity and bioavailability of baicalin. Besides, the utilization of nanotechnology to improve the bioavailability of baicalin is also mentioned.","PeriodicalId":91758,"journal":{"name":"Journal of nutritional medicine and diet care","volume":"2 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2016-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"18","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of nutritional medicine and diet care","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23937/2572-3278.1510011","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 18
Abstract
The dried root of Baikal skullcap (Scutellaria baicalensis) has been historically and widely used in traditional Eastern medicine. Modern science proved that baicalin is the major bioactive responsible for the physiological activity of Baikal skullcap. Baicalin, a flavonoid found in several species in the genus Scutellaria, has been regarded as a potent anticancer agent. In this review, we present the main extraction methods, anticancer activity and bioavailability of baicalin. Besides, the utilization of nanotechnology to improve the bioavailability of baicalin is also mentioned.