Molecular Interactions of lncRNAs: Cellular Fate Determination and Tissue Regeneration

M. Bahrami, Muhammad Irfan-maqsood
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引用次数: 0

Abstract

LncRNAs (long non-coding RNAs) are responsible to control the degradation process, RNA stability, orchestration, inhibition, transcription and histone modification etc. These RNAs have been termed as the key agents of several mechanisms such as development, organogenesis and regeneration of damaged tissues etc. They interact with a number of partner molecules either protein, RNAs or DNAs and control the cellular behaviour while differentiation or maintaining the stem cell status. This editorial is discussing the significance of lncRNAs as therapeutic target in stem cell therapy field.
lncrna的分子相互作用:细胞命运决定和组织再生
LncRNAs(长链非编码RNA)负责控制降解过程、RNA稳定性、编排、抑制、转录和组蛋白修饰等。这些rna被认为是发育、器官发生和受损组织再生等机制的关键因子。它们与许多伙伴分子相互作用,包括蛋白质、rna或dna,并在分化或维持干细胞状态时控制细胞行为。这篇社论讨论了lncRNAs作为治疗靶点在干细胞治疗领域的意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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