Sentinel Lymph Node Detection In Patients With Cervical Cancer

Abstract

We investigated the validity of sentinel lymph node (SLN) detection after radioactive isotope and/or blue dye injection in patients with cervical cancer. Between December 2013 and September 2018, 15 patients with cervical cancer FIGO stage I, II and II under went SLN detection during primary operation (radical laparoscopic hysterectomy) or in patients with non surgical stages to determine the condition of the nodes before radiotherapy. The detection rate of SLN was 100%. The false-positive rate was 0%. After the combined injection, the detection rate, especifcity, and positive predictive values were 100%. A mean of 2.7 pelvic SLNs were detected. We conclude that the combination of radioactively labeled albumin with blue dye allows successful detection of SLN in patients with cervical cancer. The clinical validity of this technique must be evaluated prospectively.