Kiyohiro Kasahara, Y. Yajima, C. Ikeda, I. Kamiyama, T. Takaki, T. Kakizawa, T. Shibahara
{"title":"Systemic Inflammatory Response Syndrome and postoperative complications after orthognathic surgery.","authors":"Kiyohiro Kasahara, Y. Yajima, C. Ikeda, I. Kamiyama, T. Takaki, T. Kakizawa, T. Shibahara","doi":"10.2209/TDCPUBLICATION.41.187","DOIUrl":null,"url":null,"abstract":"Symptoms of Systemic Inflammatory Response Syndrome (SIRS) presenting immediately after surgery have lately been regarded as potential warnings of impending postoperative complications and multiple organ failure. Reports discussing the relationship between operative stress and SIRS are found in the field of digestive surgery, but not in that of oral surgery. Sixty-five patients with jaw deformity who had undergone maxillary and mandibular orthognathic surgery (Le Fort I osteotomy and sagittal splitting ramus osteotomy) between September 2003 and October 2006 were involved in this study. A search based on the SIRS diagnostic criteria resulted in assignment of 33 cases to the SIRS group and 32 cases to the non-SIRS group. Postoperative complications occurred in 27.3% of the SIRS group and 0.0% of the non-SIRS group (p<0.01). In four cases, a postoperative fluctuation in IL-6 level evaluated. These results suggest the importance of careful management of postoperative SIRS patients in preventing complications.","PeriodicalId":45490,"journal":{"name":"Bulletin of Tokyo Dental College","volume":"50 1 1","pages":"41-50"},"PeriodicalIF":0.5000,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2209/TDCPUBLICATION.41.187","citationCount":"12","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of Tokyo Dental College","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2209/TDCPUBLICATION.41.187","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
引用次数: 12
Abstract
Symptoms of Systemic Inflammatory Response Syndrome (SIRS) presenting immediately after surgery have lately been regarded as potential warnings of impending postoperative complications and multiple organ failure. Reports discussing the relationship between operative stress and SIRS are found in the field of digestive surgery, but not in that of oral surgery. Sixty-five patients with jaw deformity who had undergone maxillary and mandibular orthognathic surgery (Le Fort I osteotomy and sagittal splitting ramus osteotomy) between September 2003 and October 2006 were involved in this study. A search based on the SIRS diagnostic criteria resulted in assignment of 33 cases to the SIRS group and 32 cases to the non-SIRS group. Postoperative complications occurred in 27.3% of the SIRS group and 0.0% of the non-SIRS group (p<0.01). In four cases, a postoperative fluctuation in IL-6 level evaluated. These results suggest the importance of careful management of postoperative SIRS patients in preventing complications.
手术后立即出现的全身性炎症反应综合征(SIRS)症状最近被认为是即将发生的术后并发症和多器官衰竭的潜在警告。讨论手术应激与SIRS之间关系的报告见于消化外科领域,但未见于口腔外科领域。本研究纳入了2003年9月至2006年10月间行上颌和下颌骨正颌手术(Le Fort I型截骨术和矢状分叉支截骨术)的65例颌骨畸形患者。基于SIRS诊断标准的搜索结果将33例分配到SIRS组,32例分配到非SIRS组。SIRS组术后并发症发生率为27.3%,非SIRS组为0.0% (p<0.01)。在4例中,评估了术后IL-6水平的波动。这些结果提示对SIRS术后患者进行精心管理对于预防并发症的重要性。