Retinoblastoma Case: Shall we Get A Paramagnetic Trend in Chemotherapy?

Alrx, er A. Bukhvostov, A. Dvornikov, K. Ermakov, D. Kuznetsov
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引用次数: 14

Abstract

We have performed our study on a NEN-treated RB cell culture derived from a real clinical autopsy material. 3.5- year-old male donor has died of a massive complex abdominal trauma being previously RB-diagnosed with NMR and ultrasound tests, tumor located behind the eye globe equator line. This is a first report ever on magnetic isotope effects of metal ions to cause the clear anti-cancer consequences in retinoblastoma cells by depriving them of the DNA repair capabilities. Both molecular mechanism of phenomenon and its possible meaning for retinoblastoma chemotherapy are presented here.
视网膜母细胞瘤病例:化疗是否需要顺磁趋势?
我们对来自真实临床尸检材料的经nen处理的RB细胞培养物进行了研究。一名3.5岁的男性捐赠者死于严重复杂的腹部创伤,此前通过核磁共振和超声检查进行了rb诊断,肿瘤位于眼球赤道线后。这是首次报道金属离子的磁性同位素效应,通过剥夺视网膜母细胞瘤细胞的DNA修复能力,从而导致其明显的抗癌效果。本文就这一现象的分子机制及其在视网膜母细胞瘤化疗中的可能意义进行综述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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