Hepatic Failure in a Patient with Metastatic Lung Cancer after Experiencing Partial Response during Chemotherapy and Immunotherapy

M. G. Gramaje, C. G. Lorenzo, A. I. D. H. Santabaya, J. Sarto
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Abstract

We present the case of a 62-year-old patient who developed dyspnoea, chest and dorsal pain. The history was taken, finds patients was smoker and has high blood pressure, chronic obstructive pulmonary disease and sleep apnea syndrome. So, the patients followed by Complementary tests (tomography, bronchoscopy and endoscopic ultrasound. he was diagnosed with lung adenocarcinoma stage IV (T4N3M1b bone and pulmonary lesions, no liver masses) without target driver. He was stared chemotherapy and immunotherapy in clinical trial with tumor response but liver failure. We performed a differential diagnosis to discern the etiology of the fulminant hepatitis.
在化疗和免疫治疗期间经历部分反应的转移性肺癌患者的肝衰竭
我们提出的情况下,62岁的病人谁发展呼吸困难,胸部和背部疼痛。记录病史,发现患者吸烟,有高血压,慢性阻塞性肺疾病和睡眠呼吸暂停综合征。因此,患者随后进行了补充检查(断层扫描、支气管镜检查和内窥镜超声检查)。诊断为肺腺癌IV期(T4N3M1b骨及肺病变,无肝肿块),无靶驱动。临床开始化疗和免疫治疗,肿瘤有反应,但肝功能衰竭。我们进行了鉴别诊断,以辨别暴发性肝炎的病因。
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