Pelargonium graveolens (Rose Geranium) - A Novel Therapeutic Agent for Antibacterial, Antioxidant, Antifungal and Diabetics

R. Hamidpour, S. Hamidpour, M. Hamidpour, Victoria Marshall, Roxanna Hamidpour
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引用次数: 25

Abstract

Objectives: Draw upon published research articles for evidence and comprise the collected evidence in an evaluation of the preserving and therapeutic abilities of Pelargonium graveolens. Design: The articles used as research for this research review were discovered by searching public databases with keywords such as “Pelargonium graveolens”, “P. graveolens”, “pelargoniums”, “rose-scented geranium”, and “geraniums.” Then the articles were reviewed, summarized, and organized based on findings. Results: Many articles were reviewed and many different benefits to the Pelargonium genus were discovered. The major focus in the reviewed articles, however, was on the species Pelargonium graveolens (P. graveolens). P. graveolens displayed many positive benefits. The major benefits that were reviewed were the plant’s antibacterial, antioxidant and anti-fungal activities. Other noteworthy benefits that were reviewed include hypoglycemic and anti-reprotoxic activities as well as fairly low toxicity levels. Conclusion: Pelargonium graveolens antibacterial activity shows promise and could move to human trials. However, more research needs to be performed on Gram-negative bacteria because the essential from the plant does not have as strong of an effect as it does on Gram-positive bacteria. As an antioxidant, results are very positive and human trials could ensue. Regarding anti-fungal activity, the essential oil outperformed the drugs currently in place to treat fungal activity and in doing so led to the conclusion that P. graveolens could be used as a viable anti-fungal. Pelargonium graveolens’s antioxidant ability is linked to its hypoglycemic effects against diabetes as diabetes has been linked to oxidative stress. Human trials in this area could also ensue. Against toxins that affected the male reproductive system, P. graveolens showed to reverse the negative effects and more research should be done to look into the potential for human trials. In most cases thus far observed, P. graveolens’s toxicity level was relatively low and within limits to be harmless to humans. However, it was not low enough to be considered without any hesitation and more research should be performed to look for ways to lower this level.
天竺葵——一种新型的抗菌、抗氧化、抗真菌和糖尿病治疗剂
目的:利用已发表的研究文章作为证据,并将收集到的证据纳入对天竺葵的保存和治疗能力的评估。设计:本研究综述的研究文献通过检索公共数据库,检索关键词为“Pelargonium graveolens”、“P.;“天竺葵”、“天竺葵”、“玫瑰天竺葵”和“天竺葵”。然后根据调查结果对文章进行审查、总结和组织。结果:查阅了许多文献,发现了天竺葵属植物的许多不同的益处。然而,所综述的文章主要关注的是Pelargonium graveolens (P. graveolens)。坟墓草显示出许多积极的益处。主要的好处是植物的抗菌,抗氧化和抗真菌活性。其他值得注意的好处包括低血糖和抗生殖毒性活性以及相当低的毒性水平。结论:天竺葵抗菌活性良好,可进行人体试验。然而,需要对革兰氏阴性菌进行更多的研究,因为植物中的必需物质对革兰氏阳性菌的作用不如它对革兰氏阳性菌的作用那么强。作为一种抗氧化剂,结果是非常积极的,人体试验可能会随之而来。在抗真菌活性方面,该精油的抗真菌活性优于目前已有的治疗真菌活性的药物,因此得出结论,该精油可以作为一种可行的抗真菌药物。天竺葵的抗氧化能力与它对糖尿病的降糖作用有关,因为糖尿病与氧化应激有关。这方面的人体试验也可能随之而来。对于影响男性生殖系统的毒素,P. graveolens显示可以逆转负面影响,应该做更多的研究来研究人体试验的可能性。在迄今观察到的大多数病例中,P. graveolens的毒性水平相对较低,在对人体无害的限度内。然而,它还没有低到可以毫不犹豫地考虑的程度,应该进行更多的研究以寻找降低这一水平的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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