Feline leukemia as a still relevant problem in domestic and wild animals – the current state of knowledge

IF 0.4 4区农林科学 Q4 VETERINARY SCIENCES

Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice Pub Date : 2023-01-01 DOI:10.21521/mw.6770

Joanna Zdziennicka, Dominika Dobko, Beata Drzewiecka, Katarzyna Krać, Aleksandra Kozera, Dominika Nguyen Ngoc, J. Wessely-Szponder

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引用次数: 0

Abstract

The aim of this review is to present information about leukemia caused by feline leukemia virus (FeLV) infection in felids. Despite widespread vaccinations, leukemia is still one of the most common diseases in cats. FeLV infection occurs by direct contact between animals, especially through contact with saliva. Infection with this highly contagious virus is characterized by immunosuppression and non-specific signs, such as cytopenia or tumorigenesis. The virus is transmitted horizontally through close contact between cats and vertically from infected queens to their kittens. Persistently infected cats are the reservoir of the virus. Rapid ELISA tests and immunochromatography play a major role in diagnosis, but RT-PCR is the most reliable diagnostic method. There is no specific therapy against FeLV, so treatment is mainly symptomatic. Research on the use of antiviral drugs, i.e. tenofovir, raltegravir, and fozyvudine, is underway. Proper prophylaxis, including regular vaccination of animals, is important to minimize the risk and consequences of infection

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猫白血病作为一个在家养和野生动物中仍然相关的问题-目前的认识状况

本文综述了猫科动物白血病病毒(FeLV)感染引起的白血病的研究进展。尽管广泛接种疫苗，白血病仍然是猫最常见的疾病之一。FeLV感染发生在动物之间的直接接触，特别是通过唾液接触。感染这种高传染性病毒的特点是免疫抑制和非特异性体征，如细胞减少或肿瘤发生。该病毒通过猫之间的密切接触水平传播，并通过受感染的母猫向其小猫垂直传播。持续感染的猫是病毒的宿主。快速ELISA检测和免疫层析在诊断中起主要作用，但RT-PCR是最可靠的诊断方法。目前尚无针对FeLV的特异性治疗方法，因此治疗主要是对症治疗。目前正在研究使用抗病毒药物，即替诺福韦、雷替格拉韦和福西夫定。适当的预防措施，包括定期为动物接种疫苗，对于尽量减少感染的风险和后果非常重要

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice VETERINARY SCIENCES-

CiteScore

0.80

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： "Medycyna Weterynaryjna" publishes various types of articles which are grouped in the following editorial categories: reviews, original studies, scientific and professional problems, the history of veterinary medicine, posthumous memoirs, as well as chronicles that briefly relate scientific advances and developments in the veterinary profession and medicine. The most important are the first two categories, which are published with short summaries in English. Moreover, from 2001 the editors of "Medycyna Weterynaryjna", bearing in mind market demands, has also started publishing entire works in English. Since 2008 the periodical has appeared in an electronic version. The following are available in this version: summaries of studies published from 1999 to 2005, full versions of all the studies published in the years 2006-2011 (in pdf files), and full versions of the English studies published in the current year (pdf). Only summaries of the remaining studies from the current year are available. In accordance with the principles accepted by the editors, the full versions of these texts will not be made available until next year. All articles are evaluated twice by leading Polish scientists and professionals before they are considered for publication. For years now "Medycyna Weterynaryjna" has maintained a high standard thanks to this system. The review articles are actually succinct monographs dealing with specific scientific and professional problems that are based on the most recent findings. Original works have a particular value, since they present research carried out in Polish and international scientific centers.