Oral and nasal vaccination: current prospects, challenges, and impact of nanotechnology-based delivery systems

IF 0.6 4区医学 Q4 PHARMACOLOGY & PHARMACY

Brazilian Journal of Pharmaceutical Sciences Pub Date : 2023-05-08 DOI:10.1590/s2175-97902023e21769

Natália Floriano Paiva, F. Vicentini

引用次数: 0

Abstract

Abstract Currently, mucosal vaccine administration has stood out as an easier and non-invasive application method. It can also be used to induce local and systemic immune responses. In the COVID-19 pandemic context, nasal and oral vaccines have been developed based on different technological platforms. This review addressed relevant aspects of mucosal vaccine administration, with emphasis on oral and nasal vaccinations, in addition to the importance of using nanotechnology-based delivery systems to enable these strategies.

查看原文本刊更多论文

口服和鼻腔疫苗接种:目前的前景、挑战和基于纳米技术的递送系统的影响

目前，粘膜疫苗给药作为一种较为简便、无创的应用方法而备受关注。它也可用于诱导局部和全身免疫反应。在COVID-19大流行背景下，基于不同的技术平台开发了鼻用和口服疫苗。这篇综述讨论了粘膜疫苗给药的相关方面，重点是口服和鼻腔疫苗接种，以及使用基于纳米技术的递送系统来实现这些策略的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Brazilian Journal of Pharmaceutical Sciences PHARMACOLOGY & PHARMACY-

CiteScore

1.40

自引率

0.00%

发文量

165

审稿时长

7.5 months

期刊介绍： The Brazilian Journal of Pharmaceutical Sciences accepts for publication Original Papers applicable to the fields of Pharmaceutical Sciences; Reviews and Current Comment Articles, which are published under the Scientific Editor and Associate Editors invitation to recognized experts or when they are spontaneously submitted by the authors in the form of abstracts to have their importance evaluated. A critical view of the subject with insertions of results of previous works in the field in relation to the state of art must be included; Short Communications reporting new methods and previews of works on researches of outstanding importance in which originality justify a quick publication. A maximum of 2000 words excluding tables, figures and references is an acceptable limit. One table, one figure and ten references may be added, and Book Reviews of the latest editions of books, prepared by specialists invited by the Scientific Editor and Associate Editors. Thematic Supplements as well as those related to scientific meetings can be published under the Scientific Editor and/or Associate Editors agreement.