Functional gastrointestinal disorders in infants: is it possible to treat them with infant formulas?

Q3 Medicine

Voprosy Prakticheskoi Pediatrii Pub Date : 2022-01-01 DOI:10.20953/1817-7646-2022-1-157-166

I.N.Kholodova I.N.Kholodova, E.S.Kiseleva E.S.Kiseleva

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引用次数: 0

Abstract

The etiology, pathogenesis, and characteristics of neonatal colic are being actively explored by clinicians and researchers. The impact of nutrition on colic in newborns is still not fully understood and requires further investigations. This article discusses the role of functional nutrients of infant formulas (including prebiotics and probiotics) in the prevention and correction of colic in newborns and their impact on the formation of the intestinal microbiota. It also focuses on the effect of prebiotics in the diet on the intestinal microbiome composition, severity of colic in newborns, and association between the presence of probiotic cultures in the diet and development of colic. We emphasize the importance of studying microbiome composition and metabolites produced by intestinal commensals, including short-chain fatty acids. We also describe possible prebiotic and probiotic effects of infant formula containing goat milk. Key words: infantile colic, infant formula, prebiotics, prebiotics, oligosaccharides 2'-FL, GOS, Bifidobacterium lactis, gut microbiota, goat milk

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婴儿功能性胃肠疾病:是否可以用婴儿配方奶粉治疗?

新生儿绞痛的病因、发病机制和特点正被临床医生和研究人员积极探索。营养对新生儿肠绞痛的影响尚不完全清楚，需要进一步调查。本文讨论了婴儿配方奶粉中功能性营养素(包括益生元和益生菌)在预防和纠正新生儿肠绞痛中的作用及其对肠道菌群形成的影响。它还侧重于饮食中益生元对肠道微生物组组成的影响，新生儿肠绞痛的严重程度，以及饮食中益生菌培养物的存在与肠绞痛发展之间的关系。我们强调研究肠道共生菌产生的微生物组组成和代谢物的重要性，包括短链脂肪酸。我们还描述了含有羊奶的婴儿配方奶粉可能产生的益生元和益生菌效应。关键词:婴儿肠绞痛，婴儿配方奶粉，益生元，益生元，低聚糖2′-FL, GOS，乳酸双歧杆菌，肠道菌群，羊奶

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来源期刊

Voprosy Prakticheskoi Pediatrii Medicine-Pediatrics, Perinatology and Child Health

CiteScore

1.20

自引率

0.00%

发文量