Pilot Study of “Classic” 3:1 Ketogenic Diet Complete Meal Replacement Treatment of Obesity-Related Type 2 Diabetes

Abstract

Introduction: Low carbohydrate (CH) diets have been used in the management of obesity-related T2DM, with modest results. “Classic” ketogenic diets (KD) used in epilepsy are very low CH (10-20 g/day), very high fat (87-90% of calories) diets. We report a pilot study of treatment of obesity-related T2DM with “classic” 3:1 [fat]:[carbohydrate + protein] weight ratio diet using the novel approach of a complete ready-made meal replacement program.