Colonic stenting in the management of acute left-sided malignant colonic obstruction is oncologically safe?

D. Belinda, Catena Fausto
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Abstract

The management of patients presenting with acute large bowel obstructioncaused by left sided colorectal cancer is still debated.Colonic stenting (CS) seems to be a good therapeutical option toemergency surgery: it is able to convert an urgent situation in anelective one. Lately conflicting results were published about thistechnique used as bridge to surgery in comparison with the emergencysurgery in terms of oncologic safety and recurrence rate.Actually self expandable metallic stents (SEMS) are not “allowed”to treat potentially curable patients. Data reported in literatureshow that colonic stenting improves primary anastomosis ratewith a low stoma creation in comparison with emergency surgery,enhancing patients’ quality of life, without differences in terms ofmortality and morbidity rate. According to available data, at oneyear follow up time, the recurrence rate is higher in patients treatedwith stent, with no statistical difference in terms of disease freesurvival and overall survival.Endoscopist’s experience, type of colic obstruction (partial or total),type of stent, insertion technique and timing of surgery arefundamental to reach CS technical and clinical success.Oncologic (un)-safety of colonic stenting has to be still investigatedand confirmed by medium and long term follow up of largeprospective studies and randomized controlled trials comparingSEMS and ES.
结肠支架置入术治疗急性左侧恶性结肠梗阻是否安全?
左侧结直肠癌引起的急性大肠梗阻患者的处理仍然存在争议。结肠支架植入术(CS)似乎是急诊手术的一个很好的治疗选择:它能够将紧急情况转化为选择性情况。最近发表的关于该技术作为外科手术的桥梁与急诊手术在肿瘤安全性和复发率方面的结果相互矛盾。实际上,自膨胀金属支架(SEMS)不被允许用于治疗可能治愈的患者。文献报道的数据显示,与急诊手术相比,结肠支架植入术在低造口率下提高了一期吻合率,提高了患者的生活质量,死亡率和发病率没有差异。根据现有资料,随访1年,支架治疗患者复发率较高,无病生存期和总生存期无统计学差异。内镜医师的经验、肠梗阻类型(部分或全部)、支架类型、插入技术和手术时机是CS技术和临床成功的基础。结肠支架植入术的肿瘤学(非)安全性仍需通过中期和长期随访的大型前瞻性研究和随机对照试验来比较sems和ES。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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