{"title":"Vaccination of corneal herpes (HSK)","authors":"Kozaburo Hayashi","doi":"10.15761/NFO.1000253","DOIUrl":null,"url":null,"abstract":"Attenuated HSV-2 (HSV TK-) has been inoculated in the deep nasal mucosa where the attenuated virus proliferated. Subsequently, it elicited educated CD4T+ cells jn the nasal mucosa but not in local dorsal lymph nodes. These CD4 T cells migrated to the vaginal mucosa and educated cervical and/or vaginal mucosal B cells to secrete secretary IgA. However, application of these protocols to the corneal herpes (HSK), there are many pit falls in these projects. Olfactory nerve","PeriodicalId":91933,"journal":{"name":"New frontiers in ophthalmology (London)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"New frontiers in ophthalmology (London)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15761/NFO.1000253","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Attenuated HSV-2 (HSV TK-) has been inoculated in the deep nasal mucosa where the attenuated virus proliferated. Subsequently, it elicited educated CD4T+ cells jn the nasal mucosa but not in local dorsal lymph nodes. These CD4 T cells migrated to the vaginal mucosa and educated cervical and/or vaginal mucosal B cells to secrete secretary IgA. However, application of these protocols to the corneal herpes (HSK), there are many pit falls in these projects. Olfactory nerve