{"title":"The impact of obesity on the short-term efficacy of inter sphincteric resection for patients with ultra-low rectal or anal canal cancer","authors":"X. Wang, J. Liu, X. Lv, Z. Gan, L. Li","doi":"10.15761/icm.1000157","DOIUrl":null,"url":null,"abstract":"Aim: To determine whether obesity has an impact on the short-term efficacy of inter sphincteric resection (ISR) for patients with ultra-low rectal or anal canal cancer. Methods: This retrospective study includes 276 patients with rectal or anal canal cancer who received treatment from the Rectal Surgery Group of the Gastrointestinal Surgery Center of West China Hospital. According to the WHO, the overweight has a BMI greater than 25. We compare the intraoperative related indicators, postoperative recovery indicators and the rate of occurrence of complications between Group A and Group B. Results: The time of operation in Group B is apparently longer than that in Group A (143.41 min VS. 130.91 min P < 0.05), the intraoperative blood loss, the anastomotic patterns and the reconstruction pattern are not statistically different. The rate of perianal infection of Group B is significantly higher than that of Group A (6.5% VS. 1.5% P < 0.05), and the rate of incision infection of Group B is significantly higher than that of Group A (5.6% VS. 0.6% P < 0.05). The rate of occurrence of other complications between two groups is not statistically different. Conclusion: Obesity increases the difficulty of performing ISR for ultra-low rectal or anal canal cancers, extends the time of operation, and increases the incidence rate of perianal infection post-operatively. There is no significant difference between the indications of postoperative recovery, and the incidence rate of complications in obese patients and that in normal weight patients. In terms of the short-term effects, the operations for obese patients are safe and effective. *Correspondence to: LI L, Way-nan Guo-Xue Xiang 37#, Chengdu, Sichuan, 610041, China, Tel: 86-18980601487; E-mail: drlili116@126.com","PeriodicalId":91880,"journal":{"name":"Integrative clinical medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Integrative clinical medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15761/icm.1000157","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Aim: To determine whether obesity has an impact on the short-term efficacy of inter sphincteric resection (ISR) for patients with ultra-low rectal or anal canal cancer. Methods: This retrospective study includes 276 patients with rectal or anal canal cancer who received treatment from the Rectal Surgery Group of the Gastrointestinal Surgery Center of West China Hospital. According to the WHO, the overweight has a BMI greater than 25. We compare the intraoperative related indicators, postoperative recovery indicators and the rate of occurrence of complications between Group A and Group B. Results: The time of operation in Group B is apparently longer than that in Group A (143.41 min VS. 130.91 min P < 0.05), the intraoperative blood loss, the anastomotic patterns and the reconstruction pattern are not statistically different. The rate of perianal infection of Group B is significantly higher than that of Group A (6.5% VS. 1.5% P < 0.05), and the rate of incision infection of Group B is significantly higher than that of Group A (5.6% VS. 0.6% P < 0.05). The rate of occurrence of other complications between two groups is not statistically different. Conclusion: Obesity increases the difficulty of performing ISR for ultra-low rectal or anal canal cancers, extends the time of operation, and increases the incidence rate of perianal infection post-operatively. There is no significant difference between the indications of postoperative recovery, and the incidence rate of complications in obese patients and that in normal weight patients. In terms of the short-term effects, the operations for obese patients are safe and effective. *Correspondence to: LI L, Way-nan Guo-Xue Xiang 37#, Chengdu, Sichuan, 610041, China, Tel: 86-18980601487; E-mail: drlili116@126.com
目的:探讨肥胖对超低位直肠癌或肛管癌患者行括约肌间切除术(ISR)短期疗效的影响。方法:回顾性研究华西医院胃肠外科中心直肠外科组收治的276例直肠肛管癌患者。根据世界卫生组织的说法,超重的人的身体质量指数大于25。比较A组与B组术中相关指标、术后恢复指标及并发症发生率。结果:B组手术时间明显长于A组(143.41 min VS. 130.91 min P < 0.05),术中出血量、吻合方式及重建方式均无统计学差异。B组肛周感染率显著高于A组(6.5% VS. 1.5% P < 0.05),切口感染率显著高于A组(5.6% VS. 0.6% P < 0.05)。两组间其他并发症发生率无统计学差异。结论:肥胖增加了超低位直肠癌或肛管癌行ISR的难度,延长了手术时间,并增加了术后肛周感染的发生率。肥胖患者术后恢复指征、并发症发生率与正常体重患者无明显差异。从短期效果来看,肥胖患者的手术是安全有效的。*通讯地址:四川省成都市卫南国学巷37号李丽,电话:86-18980601487;电子邮件:drlili116@126.com