The role of melatonin in modulating parasite infections

Aline C. França‐Botelho
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Abstract

In giardiasis, serum melatonin levels are elevated in these patients; this suggests a positive correlation between the level of melatonin and phagocytic activity in infected patients, possibly related to melatonin’s immunomodulatory effect [2]. The study in vitro showed que phagocytes exhibited higher rates of Giardia lamblia elimination when treated with melatonin. In the group of older mothers, colostrum MN phagocytes treated with melatonina obtained a higher microbicidal index for G. lamblia [6].
褪黑素在调节寄生虫感染中的作用
贾第虫病患者血清褪黑素水平升高;这表明感染患者体内褪黑素水平与吞噬活性呈正相关,可能与褪黑素的免疫调节作用[2]有关。体外研究表明,当用褪黑素治疗时,que吞噬细胞表现出更高的蓝氏贾第鞭毛虫消除率。在大龄母鼠组中,褪黑素处理的初乳MN吞噬细胞对兰氏螺旋体有较高的杀微生物指数。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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