Rapid and Safe Correction of Vitamin B12 Deficiency using Novel Methylcobalamin Nasal Spray

T. Seth, Suri, D. Balat, S. Murthy, A. Agarwal, P. Pandurangan, P. Chakrabarti, A. Maseeh, Patel Kr
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Abstract

Background & Aims: Methylcobalamin nasal spray (NasoB12® ) has been developed to overcome the drawbacks of currently available therapeutic options like the poorly absorbed oral route and the painful intramuscular route. The present study was designed to evaluate the safety and efficacy of NasoB12® in patients with Vitamin B12 deficiency, with serum vitamin B12 (svB12) <200 pg/mL (148 pmol/L).
新型甲钴胺素鼻喷雾剂快速安全纠正维生素B12缺乏症
背景与目的:甲钴胺素鼻喷雾剂(NasoB12®)的开发是为了克服目前可用的治疗方案的缺点,如口服吸收不良和肌肉注射疼痛。本研究旨在评估NasoB12®对血清维生素B12 (svB12) <200 pg/mL (148 pmol/L)的维生素B12缺乏症患者的安全性和有效性。
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